DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a21 and CYP709B3

DIOPT Version :9

Sequence 1:	NP_611003.2	Gene:	Cyp6a21 / 36665	FlyBaseID:	FBgn0033981	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_194501.1	Gene:	CYP709B3 / 828885	AraportID:	AT4G27710	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	530	Identity:	125/530 - (23%)
Similarity:	230/530 - (43%)	Gaps:	101/530 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VGTV-LLTALLALVGYLLMK-WRS----------TMRHWQDLGIPCEEPHILMGSMKGVRTARS- 54
            :.|: |||.:|.|  :::.| |::          ..:.::..||...:..||.|::..::..:.
plant     4 ISTINLLTIVLLL--FVVSKIWKACWILLLRPLMLSKRFKKQGISGPKYKILYGNLSEIKKMKKE 66

  Fly    55 -------------FNEIWTSYYNKFRGSGPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRG 106
                         |..::..|:......|....|:...:|.:::....||||:|..:|      |
plant    67 ADLCVLDPNSNDIFPRVFPQYHQWMSQYGDTFLFWTGTKPTIYISNHELAKQVLSSKF------G 125

  Fly   107 F----FHNPEDDPLSGQ-LFLLDGQKWRTMRNKLSSTFTSGKMKYMFPTV----VKVANEFTDV- 161
            |    ...||...|.|: |..:.|..|...|..|:..|:..::|.|...:    :::..|:...
plant   126 FTIIPVKRPEVFILFGKGLSFIQGDDWIRHRRILNPAFSMDRLKAMTQPMGDCTLRIFEEWRKQR 190

  Fly   162 -FGQNVAKSPVVEVRELLARFTTDVIGTCAF------GIE-CSSLKDPDAEFREMGRRSLTEQRL 218
             .|:.:.|   :|:.:...:.|.|:|.|.||      ||| |.|    ..|..:....|||...:
plant   191 RNGEVLIK---IEISKEFHKLTADIIATTAFGSSYAEGIELCRS----QTELEKYYISSLTNVFI 248

  Fly   219 GPVGIGFVNSFPNLAR-RLHMKMTAEPIERFFMRIVRETVAFREQNNIRRNDFMDQLIDLKNKPL 282
              .|..::.:..||.. .||.|     ::....||:..    |.::..:...:.|.|:.:.   |
plant   249 --PGTQYLPTPTNLKLWELHKK-----VKNSIKRIIDS----RLKSKCKTYGYGDDLLGVM---L 299

  Fly   283 MVSQSGE-SVNLTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCN 346
            ..::|.| ...:.::||..:...|:.||..|:|..:.:....|:.:|..|.::|   :||..:|.
plant   300 TAAKSNEYERKMRMDEIIEECKNFYYAGQGTTSILLTWTTMLLSLHQGWQEKLR---EEVFNECG 361

  Fly   347 GEL--NYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMH 409
            .:.  :.::...|..::.|:.|:||||..:..::||..:|.:| ||.:  |.||..::||...||
plant   362 KDKIPDTDTFSKLKLMNMVLMESLRLYGPVIKISREATQDMKV-GHLE--IPKGTSIIIPLLKMH 423

  Fly   410 RDEKLYA-NPNTFNPDNFS---------PERVKERDSVEWLPFGDGPRNCIGMRFGQMQARIGLA 464
            ||:.::. :...|||..|.         |..:        |||..|||.||...|..::|:..|.
plant   424 RDKAIWGEDAEQFNPLRFENGISQATIHPNAL--------LPFSIGPRACIAKNFAMVEAKTVLT 480

  Fly   465 LLIKDFKFSV 474
            ::::.|:.|:
plant   481 MILQQFQLSL 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	p450	35..499	CDD:278495	115/486 (24%)
CYP709B3	NP_194501.1	p450	9..517	CDD:299894	124/525 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900