DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a21 and CYP97B3

DIOPT Version :9

Sequence 1:	NP_611003.2	Gene:	Cyp6a21 / 36665	FlyBaseID:	FBgn0033981	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_193247.2	Gene:	CYP97B3 / 827177	AraportID:	AT4G15110	Length:	580	Species:	Arabidopsis thaliana

Alignment Length:	548	Identity:	128/548 - (23%)
Similarity:	218/548 - (39%)	Gaps:	137/548 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 GSMKGVRTAR-SFNEIWTSYYNKFRGSGPFAGFY-WFRR----------PAVFVL--ETSLAKQI 94
            ||:..:.||. |.::::        |...|...| ||..          |..||:  :..:|:.:
plant    79 GSLGSMPTAEGSVSDLF--------GKPLFLSLYDWFLEHGGIYKLAFGPKAFVVISDPIIARHV 135

  Fly    95 LIKEFNKFT-DRGFFHNPEDDPLSGQ-LFLLDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKVANE 157
            |.:  |.|: |:|...... :|:.|: |...|...|:..|..::..|    .|.....:|||
plant   136 LRE--NAFSYDKGVLAEIL-EPIMGKGLIPADLDTWKLRRRAITPAF----HKLYLEAMVKV--- 190

  Fly   158 FTDVFGQNVAKSPVVEVRE-------------LLARFTT---DVIGTCAFGIECSSL--KDP--- 201
            |:|...:.:.||..: :||             |.|.|::   |:||...|..:..|:  :.|
plant   191 FSDCSEKMILKSEKL-IREKETSSGEDTIELDLEAEFSSLALDIIGLSVFNYDFGSVTKESPVIK 254

  Fly   202 -------DAEFREM----------GRRSLTEQRLGPVGIGFVNS-----FPNLARRLHMKMTAEP 244
                   :||.|..          .|..:..||.....:..:|.     ..| |:....:...|.
plant   255 AVYGTLFEAEHRSTFYFPYWNFPPARWIVPRQRKFQSDLKIINDCLDGLIQN-AKETRQETDVEK 318

  Fly   245 IERFFMRIVRETVAFREQNNIRRNDFMDQLIDLKNKPLMVSQSGESVNLTIEEIAAQAFVFFAAG 309
            ::.            |:..|::....:..|:|::           .|::...::.........||
plant   319 LQE------------RDYTNLKDASLLRFLVDMR-----------GVDIDDRQLRDDLMTMLIAG 360

  Fly   310 FETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCNGELNYESMKDLVYLDQVVSETLRLYTVL 374
            .||::..:.:|::.|:||.:...:.:.|...|:.:  |...|||||.|.|:..:|.|.|||:...
plant   361 HETTAAVLTWAVFLLSQNPEKIRKAQAEIDAVLGQ--GPPTYESMKKLEYIRLIVVEVLRLFPQP 423

  Fly   375 PVLNRECLEDYEVPGHPK-----YVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKER 434
            |:|.|..|:...:||..|     :.:.||..:.|....:||....:.||:.|.|:.|.  |.||.
plant   424 PLLIRRTLKPETLPGGHKGEKEGHKVPKGTDIFISVYNLHRSPYFWDNPHDFEPERFL--RTKES 486

  Fly   435 DSVE-W-----------------------LPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSVC 475
            :.:| |                       ||||.|||.|||.:|..|::.:.||:|.:  ||.|.
plant   487 NGIEGWAGFDPSRSPGALYPNEIIADFAFLPFGGGPRKCIGDQFALMESTVALAMLFQ--KFDVE 549

  Fly   476 EKTTIPMTYNKEMFLIASNSGIYLKAER 503
            .:.|...........|.:.:|::.|.:|
plant   550 LRGTPESVELVSGATIHAKNGMWCKLKR 577

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	p450	35..499	CDD:278495	126/542 (23%)
CYP97B3	NP_193247.2	PLN02738	45..580	CDD:215393	128/548 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900