DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a21 and CYP72A15

DIOPT Version :9

Sequence 1:	NP_611003.2	Gene:	Cyp6a21 / 36665	FlyBaseID:	FBgn0033981	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_001325567.1	Gene:	CYP72A15 / 820697	AraportID:	AT3G14690	Length:	547	Species:	Arabidopsis thaliana

Alignment Length:	528	Identity:	136/528 - (25%)
Similarity:	218/528 - (41%)	Gaps:	99/528 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSVGTVLLTALLALVGYLLMKWRSTMRHW------------QDL-GIPCEEPHILMGSMKG---- 48
            :||.:|.::.:||:|.:.:  ||:....|            |.| |.|...   |:|.:|.
plant    38 ISVASVTISVVLAVVSWWI--WRTLQWVWFKPKMLEHYLRRQGLAGTPYTP---LVGDLKKNFTM 97

  Fly    49 VRTARS--------------------FNEIWTSYYNKFRGSGPFAGFYWFRRPAVFVLETSLAKQ 93
            :..|||                    |.....:|:..|   ||.        |.:.:::....|:
plant    98 LSEARSKPLKLTDDISPRVVPYPLQMFKTYGRTYFTWF---GPI--------PTITIMDPEQIKE 151

  Fly    94 ILIKEFNKFTDRGFFHNPEDDPL----SGQLFLLDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKV 154
            :    |||..|   |..|...||    :..|...||.||...|..::..|...|:|.|.|...:.
plant   152 V----FNKVYD---FQKPHTFPLATIIAKGLANYDGDKWAKHRRIINPAFHIEKIKNMVPAFHQS 209

  Fly   155 ANEFTDVFGQNVA---KSPVVEVRELLARFTTDVIGTCAFGIECSSLKDPDAEFR---EMGRRSL 213
            ..|....:.|.|:   .|..|:|...|...|.|||...|||   ||.|:....|.   |:.:  |
plant   210 CREVVGEWDQLVSDKGSSCEVDVWPGLVSMTADVISRTAFG---SSYKEGQRIFELQAELAQ--L 269

  Fly   214 TEQRLGPVGIGFVNSFPNLARRLHMKMTAEPIERFFMRIVRETVAFREQNNIRRNDFMDQLIDLK 278
            ..|......|...:..|..:.| .||..|..|:.....||.:.:..||......:|.:..|::..
plant   270 IIQAFRKAFIPGYSYLPTKSNR-RMKAAAREIQVILRGIVNKRLRAREAGEAPSDDLLGILLESN 333

  Fly   279 NKPLMVSQSGESVNLTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIE 343
                  .:..|...::.|::..:..:|:.||.||:|..:.:.:..|:|:||.|.|.|:|.::|..
plant   334 ------LRQTEGNGMSTEDLMEECKLFYFAGQETTSVLLVWTMVLLSQHQDWQARAREEVKQVFG 392

  Fly   344 KCNGELNYESMKDLVYLDQVVSETLRLYTVLPVLNREC-----LEDYEVPGHPKYVIKKGMPVLI 403
              :.|.:.|.:..|..:..::.|.||||..:..|.|..     |.|..:||        |:.:.:
plant   393 --DKEPDAEGLNQLKVMTMILYEVLRLYPPVTQLTRAIHKELKLGDLTLPG--------GVQISL 447

  Fly   404 PCGAMHRDEKLYANPNT-FNPDNFSPERVK-ERDSVEWLPFGDGPRNCIGMRFGQMQARIGLALL 466
            |...:..|.:|:.|... ||||.|.....| .:..|.:.||..|||.|||..|..::|::.:||:
plant   448 PILLVQHDIELWGNDAAEFNPDRFKDGLSKATKSQVSFFPFAWGPRICIGQNFALLEAKMAMALI 512

  Fly   467 IKDFKFSV 474
            ::.|.|.:
plant   513 LRRFSFEI 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	p450	35..499	CDD:278495	124/481 (26%)
CYP72A15	NP_001325567.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900