DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a21 and CYP72A10

DIOPT Version :9

Sequence 1:	NP_611003.2	Gene:	Cyp6a21 / 36665	FlyBaseID:	FBgn0033981	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_188082.2	Gene:	CYP72A10 / 820692	AraportID:	AT3G14640	Length:	536	Species:	Arabidopsis thaliana

Alignment Length:	532	Identity:	136/532 - (25%)
Similarity:	216/532 - (40%)	Gaps:	105/532 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSVGTVLLTALLALVGYLLMKWRSTMRHW------------QDL-GIPCEEPHILMGSMKGVRTA 52
            :||..|.::.::.:|.:.:  ||:....|            |.| |.|...   |:|.:|  |..
plant    25 ISVACVTVSVVVVVVSWWV--WRTLQWVWFKPKMLESYLRRQGLAGTPYTP---LIGDLK--RNV 82

  Fly    53 RSFNEIWTSYYNKFRGS-------GPF--------AGFYWF-RRPAVFVLETSLAKQILIKEFNK 101
            ....|. ||...|....       .||        ..|.|. .:|.:.:::..|.|::    |||
plant    83 NMLTEA-TSKPIKLTEDITPRVLPHPFQMLKTHGRTFFTWLGPKPTITIMDPELIKEV----FNK 142

  Fly   102 FTDRGFFHNPEDDPLSGQLFLL-----------DGQKWRTMRNKLSSTFTSGKMKYMFP----TV 151
            ..|     .|:     .|.|||           ||.||...|..::..|...|:|.|.|    :.
plant   143 VYD-----YPK-----AQTFLLGRLIATGIINYDGDKWAKHRRIINPAFHIEKIKNMVPAFHQSC 197

  Fly   152 VKVANEFTDVFGQNVAKSPVVEVRELLARFTTDVIGTCAFGIECSSLKDPDAEFREMGRR-SLTE 215
            ..|..|::.:.....:.|..|:|...|...|.|||...|||   ||.|:....|...... .|..
plant   198 SDVVGEWSKLVSDKGSSSCEVDVWPWLVSMTGDVISRTAFG---SSYKEGQRIFELQAELVHLIL 259

  Fly   216 QRLGPVGIGFVNSFPNLARRLHMKMTAEPIERFFMRIVRETVAFREQNNIRRNDFMDQLIDLKNK 280
            |....|.|......|..:.| .||..|..|:.....||.:.:..||......|   |.|:.:
plant   260 QAFWKVYIPGYRYLPTKSNR-RMKAAAREIQVILKGIVNKRLRAREAGKAAPN---DDLLGI--- 317

  Fly   281 PLMVSQSGESV--NLTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIE 343
             |:.|..|::.  .::.|::..:..:|:.||.||:|..:.:|:..|:.:||.|.|.|:|.::|..
plant   318 -LLESNLGQAKGNGMSTEDVMEECKLFYFAGQETTSVLLVWAMVLLSHHQDWQARAREEVKQVFG 381

  Fly   344 KCNGELNYESMKDLVYLDQVVSETLRLYTVLPVLNREC-----LEDYEVPGHPKYVIKKGMPVLI 403
              :.|.:.|.:..|..:..::.|.||||..:..|.|..     |.|..:|.        |:.:.:
plant   382 --DKEPDTECLSQLKVMTMILYEVLRLYPPVTHLTRAIDKEMKLGDLTLPA--------GVHISL 436

  Fly   404 PCGAMHRDEKLYANPNTFNPDNFSPERVKE------RDSVEWLPFGDGPRNCIGMRFGQMQARIG 462
            |...:.||..|:..    :...|.|||.|:      :..|.:.||..|||.|||..|..::|::.
plant   437 PIMLVQRDPMLWGT----DAAEFKPERFKDGLSKATKSQVSFFPFAWGPRICIGQNFAMLEAKMA 497

  Fly   463 LALLIKDFKFSV 474
            :||:::.|.|.:
plant   498 MALILQTFTFEL 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	p450	35..499	CDD:278495	126/485 (26%)
CYP72A10	NP_188082.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900