DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a21 and BAS1

DIOPT Version :9

Sequence 1:	NP_611003.2	Gene:	Cyp6a21 / 36665	FlyBaseID:	FBgn0033981	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_180239.1	Gene:	BAS1 / 817212	AraportID:	AT2G26710	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	511	Identity:	136/511 - (26%)
Similarity:	218/511 - (42%)	Gaps:	82/511 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VLLTALLALV---GYLLMKW--RSTMRHWQDLGIPCEEPHILMGSMK---GVRTARSFNEI---- 58
            ::|:.:|:||   |..|:.|  |....|:...||.....|..:|::|   |:....|.:.:
plant    14 LVLSVILSLVIVKGMSLLWWRPRKIEEHFSKQGIRGPPYHFFIGNVKELVGMMLKASSHPMPFSH 78

  Fly    59 -----WTSYYNKFRGSGPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLSG 118
                 ..|:|:.:|.........||..    ....::|...||:|.  |:...|:...|..||..
plant    79 NILPRVLSFYHHWRKIYGATFLVWFGP----TFRLTVADPDLIREI--FSKSEFYEKNEAHPLVK 137

  Fly   119 Q-----LFLLDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVE--VRE 176
            |     |..|.|:||...|..:|.||....:|.:.|.|:|...:..|.:...::::..||  |.|
plant   138 QLEGDGLLSLKGEKWAHHRKIISPTFHMENLKLLVPVVLKSVTDMVDKWSDKLSENGEVEVDVYE 202

  Fly   177 LLARFTTDVIGTCAFGIECSSLKDPDAEFREMGRRSL----TEQRLGPVGIGFVNSFPNLARRLH 237
            .....|.|||...|||   ||.:|..|.||...::.|    ..|::...|..|   ||.......
plant   203 WFQILTEDVISRTAFG---SSYEDGRAVFRLQAQQMLLCAEAFQKVFIPGYRF---FPTRGNLKS 261

  Fly   238 MKMTAEPIERFFMRIVRETVAFREQNNI----------RRNDFMDQLIDLKNKPLMVSQSGESVN 292
            .|:..| |.:..::::..    |.||.|          ...|.:..:|..|             |
plant   262 WKLDKE-IRKSLLKLIER----RRQNAIDGEGEECKEPAAKDLLGLMIQAK-------------N 308

  Fly   293 LTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCNGE--LNYESMK 355
            :|:::|..:...||.||.:|:|..:.:....|:.:.:.|.:.|   .||:..|...  ...:.:.
plant   309 VTVQDIVEECKSFFFAGKQTTSNLLTWTTILLSMHPEWQAKAR---DEVLRVCGSRDVPTKDHVV 370

  Fly   356 DLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANP-N 419
            .|..|..:::|:||||..:....|....|.::.|   |.|..|..:|||..|:|.|:.::.|. |
plant   371 KLKTLSMILNESLRLYPPIVATIRRAKSDVKLGG---YKIPCGTELLIPIIAVHHDQAIWGNDVN 432

  Fly   420 TFNPDNFS---PERVKERDSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKF 472
            .|||..|:   |...|.  .|.::|||.|.|.|||.....:||::.||::|:.|.|
plant   433 EFNPARFADGVPRAAKH--PVGFIPFGLGVRTCIGQNLAILQAKLTLAVMIQRFTF 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	p450	35..499	CDD:278495	125/477 (26%)
BAS1	NP_180239.1	CYP734	85..509	CDD:410732	120/440 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810