Protein Alignment Cyp6a21 and cyp4v2b

DIOPT Version :10

• Sequence 1: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0288232
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001073465.2
• Gene: cyp4v2b / 562008
• ZFINID: ZDB-GENE-061103-88
• Length: 510
• Species: Danio rerio
• Alignment Length: 556
• Identity: 136/556 - (24%)
• Similarity: 232/556 - (41%)
• Gaps: 120/556 - (21%)

  Fly     5 TVLLTALLALVGYLLMKWRSTMRHWQDL----GIPCEEPHILMGSMKGVRTARS--FNEI----- 58
            |.:|..|||...|..:|  :.:..|.::    |:....|  ::|:....:|...  ||:|
Zfish    15 TAVLLLLLASTAYNPLK--NYIGKWNEMRPIPGMAGAYP--IIGNALQFKTNAGDFFNQIIEGTN 75

  Fly    59 ----------WTSYYNKFRGSGPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPED 113
                      |.       |..||...|......| ||..|       :..:|.....|.|
Zfish    76 ENRHLPLAKVWV-------GPVPFLILYHAENIEV-VLSNS-------RHLDKSYSYRFLH---- 121

  Fly   114 DPLSGQ-LFLLDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVREL 177
             |..|. |....|:|||..|..|:.||...    :....::|.||.||:..|.:.|   :|..|.
Zfish   122 -PWLGTGLLTSTGEKWRNRRKMLTPTFHFS----ILSDFLEVMNEQTDILIQKMQK---LEDGEP 178

  Fly   178 LARFTTDVIGTCAFGIECSSL--------KDPDAEF-REMGRRS--LTEQRLGPVGIGFVNSFPN 231
            ...|  :.|..||..|.|.:.        .:.|:|: :.:.:.|  :|:::..|.      .:|:
Zfish   179 FNCF--NFITLCALDIICETAMGKKIYAQSNADSEYVQSVYKMSDIITKRQRAPW------LWPD 235

  Fly   232 L-----------ARRLHMKMTAEPIERFFMRIVRETVAF--------REQNNIRRNDFMDQLIDL 277
            .           |:||.:      :..|...::||...|        .:|...:|..|:|.|:.
Zfish   236 WIYNKLKEGKEHAKRLKI------LHSFTANVIRERAEFMSSEPDSDSDQGGRKRQAFLDMLLK- 293

  Fly   278 KNKPLMVSQSGESVNLTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVI 342
                 ...::|:  .|:.|:|..:...|...|.:|::.:|.:||:.:..:.::|..|:.|.|||.
Zfish   294 -----TTYENGQ--KLSHEDIQEEVDTFMFEGHDTTAASMNWALHLIGSHPEVQKAVQAELQEVF 351

  Fly   343 EKCNGELNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGA 407
            ......:..|.:|.|.||:.|:.|:||::..:|:..|...|...:.|   :.:.||:..:|...|
Zfish   352 GSSERHVGVEDLKKLRYLECVIKESLRIFPSVPLFARSICEACHING---FKVPKGVNAVIIPYA 413

  Fly   408 MHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKF 472
            :|||.:.:..|..|.|:.|.||..|.|....::||..|||||||.||..|:.::.||.:::.|..
Zfish   414 LHRDPRYFPEPEEFQPERFMPENSKGRHPYAYIPFSAGPRNCIGQRFAMMEEKVVLATILRHFDV 478

  Fly   473 SVCEKTTIPMTYNKEM-----FLIASNSGIYLKAER 503
            ..|:.       .:|:     .::....||::|.:|
Zfish   479 EACQS-------REELRPLGELILRPEKGIWIKLQR 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	CYP6-like	68..498	CDD:410679	117/465 (25%)
cyp4v2b	NP_001073465.2	None