Protein Alignment Cyp6a21 and Cyp6a17

DIOPT Version :9

• Sequence 1: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0033981
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001286433.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 506
• Identity: 249/506 - (49%)
• Similarity: 334/506 - (66%)
• Gaps: 14/506 - (2%)

  Fly     6 VLLTALLALVGYLLMKWRSTMRH--WQDLGIPCEEPHILMGSMKGVRTARSFNEIWTSYYNKFRG 68
            :||.||:.::..||: :.:..||  ||..|||.:|.|.|.|::|.....|...||:..||.|::.
  Fly     1 MLLLALIVVILSLLV-FAARRRHGYWQRRGIPHDEVHPLFGNIKDWPNKRHIAEIFRDYYFKYKN 64

  Fly    69 SG-PFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLSGQLFLLDGQKWRTMR 132
            |. |||||::|......|.:..|.|::|||:||.|.:||.|:|..|||||..||.::|||||.:|
  Fly    65 SDYPFAGFFFFFTRTAVVTDMELLKRVLIKDFNHFENRGVFYNEIDDPLSATLFSIEGQKWRHLR 129

  Fly   133 NKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVA--KSPVVEVRELLARFTTDVIGTCAFGIEC 195
            :||:.||||||||.|||.||||..|...||....|  :..|:||.:|:||:|.||||.||||:.|
  Fly   130 HKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRSKTAADRGQVLEVVDLVARYTADVIGNCAFGLNC 194

  Fly   196 SSLKDPDAEFREMGRRSLTEQRLGPVGIGFVNSFPNLARRLHMKMTAEPIERFFMRIVRETVAFR 260
            :||.||.|||..:|:|::||.|.|.:...|:..||.|:|||.:|:..:..|.|:.:|||||:.:|
  Fly   195 NSLYDPKAEFVSIGKRAITEHRYGNMLDIFLFGFPKLSRRLRLKLNIQEAEDFYTKIVRETIDYR 259

  Fly   261 EQNNIRRNDFMDQLIDL-KNKPLMVSQSGESVN-LTIEEIAAQAFVFFAAGFETSSTTMGFALYE 323
            .:...:||||||.||:: ||:     |||.|.: ||..|:.||||:||.||||||||||||||||
  Fly   260 LRTKEKRNDFMDSLIEMYKNE-----QSGNSEDGLTFNELLAQAFIFFVAGFETSSTTMGFALYE 319

  Fly   324 LAQNQDIQNRVRKECQEVIEKCNGELNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVP 388
            ||:|||:|:::|:|...|..|.|.|..||.:|::.||:|||.||||.|.||..|.|....|:. |
  Fly   320 LARNQDVQDKLREEIGNVFGKHNKEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDFS-P 383

  Fly   389 GHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMR 453
            ..|||.|.||..|:||...:|.|..:|..|..|.|:.|:.|.:..|.|..|||||:|||||||:|
  Fly   384 EDPKYFIAKGTIVVIPALGIHYDPDIYPEPEIFKPERFTDEEIAARPSCTWLPFGEGPRNCIGLR 448

  Fly   454 FGQMQARIGLALLIKDFKFSVCEKTTIPMTYNKEMFLIASNSGIYLKAERV 504
            ||.||..:|||.||:.:||||..:|.|||....:..||::.:||:||.|::
  Fly   449 FGMMQTCVGLAYLIRGYKFSVSPETQIPMKIVVKNILISAENGIHLKVEKL 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	p450	35..499	CDD:278495	234/468 (50%)
Cyp6a17	NP_001286433.1	p450	36..478	CDD:278495	227/447 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471826
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	1	1.000	-	-		H130979
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	12	11.800