Protein Alignment Cyp6a21 and Cyp6d2

DIOPT Version :9

• Sequence 1: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0033981
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Alignment Length: 497
• Identity: 162/497 - (32%)
• Similarity: 262/497 - (52%)
• Gaps: 52/497 - (10%)

  Fly     5 TVLLTALLALVGYLLMKWRSTMRHWQDLGIPCEEPHILMGSMKGV-RTARSFNEIWTSYYNKFRG 68
            |:|||.|:|.:.|..:|...|  |||.||:..|...|..|.|..| :..||........|  .|.
  Fly     3 TILLTILIAGLLYRYVKRHYT--HWQRLGVDEEPAKIPFGVMDTVMKQERSLGMALADIY--ARH 63

  Fly    69 SGPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLSGQLFLLDGQKWRTMRN 133
            .|...|.|...:.::.:.:..||:||:..:|..|.|||.:.:.:.||||..||.|.|..||.:|.
  Fly    64 EGKIVGIYMLNKRSILIRDAQLARQIMTSDFASFHDRGVYVDEDKDPLSANLFNLRGASWRNLRQ 128

  Fly   134 KLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVRELLARFTTDVIGTCAFGIECSSL 198
            ||:.:|:|||:|.||.|:..|.::........:.:|..||:::::..:..|:||:..||:|..|.
  Fly   129 KLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDIIGSVIFGLEIDSF 193

  Fly   199 KDPDAEFREMGRRSLTEQRLGPVGIGFVNSFPNLARRLH-MKM-TAEPIERFFMRI--------- 252
            ::|..||||:...:..::              :|..::| |.| ...||.:...|:
  Fly   194 RNPKNEFREISSSTSRDE--------------SLLLKIHNMSMFICPPIAKLMNRLGYESRILTS 244

  Fly   253 ----VRETVAFREQNNIRRNDFMDQLIDLKNKPLMVSQSGESV-----------NLTIEEIAAQA 302
                ::.|:.|||::|:.|.|.:..||.|:|.. .:.:..:.|           :::||:|||||
  Fly   245 LRDMMKRTIEFREEHNVVRKDMLQLLIRLRNTG-KIGEDDDQVWDMETAQEQLKSMSIEKIAAQA 308

  Fly   303 FVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCN----GELNYESMKDLVYLDQV 363
            |:|:.||.|:::....|.||||:...::....::|...|:.|.|    ....||:::||.:||..
  Fly   309 FLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAVQDLKFLDIC 373

  Fly   364 VSETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSP 428
            :.||:|.|..||.|||||.|||.||| ..::|.||.|:||....|.||...:.|||.::|..|..
  Fly   374 IMETIRKYPGLPFLNRECTEDYPVPG-TNHIIAKGTPILISLFGMQRDPVYFPNPNGYDPHRFDS 437

  Fly   429 ERVKERDSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDF 470
            ..: ..|...::|||:|||:||.:|.|::.:::.:|.::.:|
  Fly   438 NNM-NYDQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANF 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	p450	35..499	CDD:278495	148/467 (32%)
Cyp6d2	NP_611698.1	p450	65..506	CDD:278495	139/431 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461159
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	237	1.000	Inparanoid score	I3345
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	10	9.900