Protein Alignment Cyp6a21 and Cyp4e2

DIOPT Version :9

• Sequence 1: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0033981
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 577
• Identity: 125/577 - (21%)
• Similarity: 235/577 - (40%)
• Gaps: 144/577 - (24%)

  Fly     6 VLLTALLALVGYLLMKWRSTMRHWQDL-------GIPCEEPHILMGSMKGVRTARSFNEIWTSYY 63
            :.|...|.||.||.:   ||.|..:.|       |:|      |||:..  :..::.:||..:.:
  Fly     7 IFLALPLLLVAYLEL---STFRRRRVLNKFNGPRGLP------LMGNAH--QMGKNPSEILDTVF 60

  Fly    64 NKFRGSGPFAGFYWFRRPA-VFV-----LETSLAKQILIKEFNKFTDRGFFHNPEDDPLSG-QLF 121
            :.:...|.....:|....: |.|     ||..|:.|.||.:.:.:.   ..|     |..| .|.
  Fly    61 SWWHQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQ---LTH-----PWLGLGLL 117

  Fly   122 LLDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAK-----------SPVVEVR 175
            ...|.||...|..::..|.           ..:..:|.:|..:|..|           ..:.:.:
  Fly   118 TSTGSKWHKHRKMITPAFH-----------FNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQ 171

  Fly   176 ELLARFTTDVIGTCAFGIECSSLKDPDAE----FREMG-----------RRSLTEQRLGPVGIGF 225
            |.....|.|||...|.|:..:::::..:.    |::|.           :|:....||.|
  Fly   172 EQAHYLTLDVICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAP----- 231

  Fly   226 VNSFPNLARRLHMKMTAEPIERFFMRIVRETVAFREQNNIRRN----------DFMDQLID--LK 278
              .:|..:|      |.:.::.|...|:.:.:...:...:..|          .|:|.|:.  :.
  Fly   232 --DYPAYSR------TLKTLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTID 288

  Fly   279 NKPLMVSQSGESVNLTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIE 343
            .:|           |..:|:..:...|...|.:|:::.:.||:|.|:::||.|.::.||.:||:.
  Fly   289 GRP-----------LNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMG 342

  Fly   344 KCNGEL----NYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIP 404
              |.||    .::.:..:.|||..:.|..|:|..:|.:.|...:||.:.|.   ::.||..:.:.
  Fly   343 --NSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGD---LVPKGTTLNLG 402

  Fly   405 CGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKD 469
            ...:..:||::.:|:.|.|:.|..|:   ....|::||..|||||||.:|..::.:..::.:|::
  Fly   403 LVMLGYNEKVFKDPHKFRPERFELEK---PGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRN 464

  Fly   470 FKF-----SVCEK-----TTI-----------PMTYNKEMFLIA-----SNSGIYLK 500
            |:.     .:..|     |||           |..:..:..|.|     |.:|:|::
  Fly   465 FEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIR 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	p450	35..499	CDD:278495	113/538 (21%)
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	105/492 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810