Protein Alignment Cyp6a21 and Cyp6u1

DIOPT Version :9

• Sequence 1: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0033981
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001286149.1
• Gene: Cyp6u1 / 35608
• FlyBaseID: FBgn0033121
• Length: 488
• Species: Drosophila melanogaster
• Alignment Length: 510
• Identity: 174/510 - (34%)
• Similarity: 268/510 - (52%)
• Gaps: 44/510 - (8%)

  Fly     7 LLTALLAL-VGYLLMKWRSTMRHWQDLGIPCEEPHILMGSMKGVRTAR-----SFNEIWTSYYNK 65
            |||||.|| |.|.|:|:  ::.:|:..||..|:|..|.|::|||.:.:     :..:|:|:|
  Fly     8 LLTALGALSVVYALVKF--SLGYWKRRGILHEKPKFLWGNIKGVVSGKRHAQDALQDIYTAY--- 67

  Fly    66 FRGSGPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLSGQLFLLDGQKWRT 130
             :|..||.|||...:|.:..|:..|..||:..:...||.||.:.||..:|||..|..|||.|||:
  Fly    68 -KGRAPFVGFYACLKPFILALDLKLVHQIIFTDAGHFTSRGLYSNPSGEPLSHNLLQLDGHKWRS 131

  Fly   131 MRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVRELLARFTTDVIGTCAFGIEC 195
            :..|.:..||...|:.:...:.::::......|:...::  :.:.||:..:.|||:.:.|||:
  Fly   132 LHAKSAEVFTPANMQKLLVRLSQISSRIQRDLGEKSLQT--INISELVGAYNTDVMASMAFGL-- 192

  Fly   196 SSLKDPDAEFREMGRRSLTEQRLGPVGIGFVNSFPNLARRLHMKMTAEPIERFFMRIVRETVAFR 260
              :...:.||.:..|....:.|:....:..  .||.:||.|..|..|||...:|.:     ||..
  Fly   193 --VGQDNVEFAKWTRNYWADFRMWQAYLAL--EFPLIARLLQYKSYAEPATAYFQK-----VALS 248

  Fly   261 EQNNIRRND------FMDQLIDLKNKPLMVSQSGESVNLTIEEIAAQAFVFFAAGFETSSTTMGF 319
            :....||.|      |: ||.....||           ||..|||.|||.|..||....:.|:.|
  Fly   249 QLQLHRRRDRQPLQTFL-QLYSNAEKP-----------LTDIEIAGQAFGFVLAGLGPLNATLAF 301

  Fly   320 ALYELAQNQDIQNRVRKECQEVIEKCNGELNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLED 384
            .|||||:..::|:|.|.|..:.:|:..|::..|.:::|.|..||::|||||:|..|.|.|...::
  Fly   302 CLYELARQPEVQDRTRLEINKALEEHGGQVTPECLRELRYTKQVLNETLRLHTPHPFLLRRATKE 366

  Fly   385 YEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNC 449
            :|||| ..:||.||..||||..|:|.|..:|.||..|.|:.|..:..:.|.:..:||||||.|.|
  Fly   367 FEVPG-SVFVIAKGNNVLIPTAAIHMDPGIYENPQRFYPERFEEQARRSRPAAAFLPFGDGLRGC 430

  Fly   450 IGMRFGQMQARIGLALLIKDFKFSVCEKTTIPMTYNKEMFLIASNSGIYLKAERV 504
            |..||.:.|..:||..|::..:::...:|:||:.|:....|:...|.|.|..|||
  Fly   431 IAARFAEQQLLVGLVALLRQHRYAPSAETSIPVEYDNRRLLLMPKSDIKLSVERV 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	p450	35..499	CDD:278495	156/474 (33%)
Cyp6u1	NP_001286149.1	p450	38..475	CDD:299894	153/466 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471845
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	9	8.900