Protein Alignment Cyp6a21 and Cyp4a12a

DIOPT Version :9

• Sequence 1: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0033981
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_803125.2
• Gene: Cyp4a12a / 277753
• MGIID: 88612
• Length: 508
• Species: Mus musculus
• Alignment Length: 536
• Identity: 127/536 - (23%)
• Similarity: 220/536 - (41%)
• Gaps: 84/536 - (15%)

  Fly     2 SVGTVLLTALLALVGYLLMKW--RSTMRHWQDLGIPCEEPHILMGSMKGVRTARSFNEIWTSYYN 64
            ||.::||........||..:|  .||.:      .|....|.|.|..  :...:...:|.|...|
Mouse    23 SVLSLLLLLFKTAQLYLHRQWLLSSTQQ------FPSPPSHWLFGHK--ILKDQDLQDILTRIKN 79

  Fly    65 KFRGSGPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLSGQLFLLDGQKWR 129
             |..:.|  .:.|..:..:.|.:....|.||.:...|......|..|.   :...|.:||||.|.
Mouse    80 -FPSACP--QWLWGSKVRIQVYDPDYMKLILGRSDPKANGSYRFLAPW---IGRGLLMLDGQTWF 138

  Fly   130 TMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVRELLARFTTDVIGTCAFGIE 194
            ..|..|:..|....:|.....:........|.:.|.|.:...:|:...:...|.|.|..|||..|
Mouse   139 QHRRMLTPAFHYDILKPYTEIMADSVRVMLDKWEQIVGQDSTLEIFRHITLMTLDTIMKCAFSHE 203

  Fly   195 CSSLKD-------------PDAEFREMGRRSLTEQ-----RLGPVGIGFVNSFPNLA-------- 233
            .|...|             .|..|..:  |::..|     |:...|.. .||...||
Mouse   204 GSVQLDRKYKSYIQAVEDLNDLVFSRV--RNIFHQNDIIYRVSSNGCK-ANSACKLAHDHTDQVI 265

  Fly   234 --RRLHMKMTAEPIERFFMRIVRETVAFREQNNIRRNDFMDQLIDLKNKPLMVSQSGESVNLTIE 296
              ||:.:: ..|.:|:...:              ||.||:|.|:..:      .::|:|  |:.:
Mouse   266 KSRRIQLQ-DEEELEKLKKK--------------RRLDFLDILLFAR------MENGKS--LSDK 307

  Fly   297 EIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCNGE---LNYESMKDLV 358
            ::.|:...|...|.:|:::.:.:..|.||.|.:.|.|.|||.|.::    |:   :.:..:..:.
Mouse   308 DLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQRCRKEIQSLL----GDGTSITWNDLDKMP 368

  Fly   359 YLDQVVSETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNP 423
            |....:.|.||:|..:|.::||.......|....  :.||:.|::....:|.:..::.||..|:|
Mouse   369 YTTMCIKEALRIYPPVPSVSRELSSPVTFPDGRS--LPKGIHVMLSFYGLHHNPTVWPNPEVFDP 431

  Fly   424 DNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSVCEKTTIPMTYNKEM 488
            ..|:|.  ..|.|..:|||..|.|||||.:|...:.::.:||.:..|:. :.:.|.:|:...:
Mouse   432 SRFAPG--SSRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFEL-LPDPTRVPIPIPR-- 491

  Fly   489 FLIASNSGIYLKAERV 504
            .::.|.:||:|..:::
Mouse   492 IVLKSKNGIHLHLKKL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	p450	35..499	CDD:278495	117/494 (24%)
Cyp4a12a	NP_803125.2	p450	52..502	CDD:278495	117/494 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900