Protein Alignment Cyp6a21 and Cyp51

DIOPT Version :10

• Sequence 1: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0288232
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_037073.1
• Gene: Cyp51 / 25427
• RGDID: 2481
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 493
• Identity: 108/493 - (21%)
• Similarity: 186/493 - (37%)
• Gaps: 64/493 - (12%)

  Fly     4 GTVLLTALLALVGYLLMKW--RSTMRHWQDLGIPCEEPHILMGSMKGVRTARSFN----EIWTSY 62
            |.:|.|.|:|....|.:.:  |..:.|...|....:.|..:...:..:..|.:|.    |...:.
  Rat    24 GNLLSTLLIACAFTLSLVYLFRLAVGHMVQLPAGAKSPPYIYSPIPFLGHAIAFGKSPIEFLENA 88

  Fly    63 YNKFRGSGPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLSGQLFLLDGQK 127
            |.|:   ||...|....:...::|.:. |..:|....|:..:....:.....|:.|:....|...
  Rat    89 YEKY---GPVFSFTMVGKTFTYLLGSD-AAALLFNSKNEDLNAEEVYGRLTTPVFGKGVAYDVPN 149

  Fly   128 WRTMRNK--LSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVRELLARFTTDVIGTCA 190
            ...:..|  |.|.......|.....:.|.|.|:...:|::..::    |.|.|:.........|.
  Rat   150 AVFLEQKKILKSGLNIAHFKQYVSIIEKEAKEYFKSWGESGERN----VFEALSELIILTASHCL 210

  Fly   191 FGIECSSLKDPDAEFREMGRRSLTE---QRLGPVGIGFVNS---------FPNLAR--RLHMKMT 241
            .|.|.              |..|.|   |....:..||.::         .|:..|  |.|.:
  Rat   211 HGKEI--------------RSQLNEKVAQLYADLDGGFSHAAWLLPGWLPLPSFRRRDRAHRE-- 259

  Fly   242 AEPIERFFMRIVRETVAFREQNNIRRNDFMDQLIDLKNKPLMVSQSGESVNLTIEEIAAQAFVFF 306
               |:..|.:.:::    |..:.....|.:..|:|...|        :...||.:|||.......
  Rat   260 ---IKNIFYKAIQK----RRLSKEPAEDILQTLLDSTYK--------DGRPLTDDEIAGMLIGLL 309

  Fly   307 AAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCNGELNYESMKDLVYLDQVVSETLRLY 371
            .||..|||||..:..:.||:::.:|::...|.:.|..:....|.||.:|||..||:.:.|||||.
  Rat   310 LAGQHTSSTTSAWMGFFLARDKPLQDKCYLEQKTVCGEDLPPLTYEQLKDLNLLDRCIKETLRLR 374

  Fly   372 TVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDS 436
            ..:..:.|.......|.|   |.|..|..|.:......|.:..:.....||||.:..:.....:.
  Rat   375 PPIMTMMRMAKTPQTVAG---YTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEK 436

  Fly   437 VEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSV 474
            ..::|||.|...|||..|..:|.:...:.:::.::|.:
  Rat   437 FAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDL 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	CYP6-like	68..498	CDD:410679	93/423 (22%)
Cyp51	NP_037073.1	CYP51-like	88..499	CDD:410668	95/429 (22%)