Protein Alignment Cyp6a21 and Tbxas1

DIOPT Version :10

• Sequence 1: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0288232
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_035669.3
• Gene: Tbxas1 / 21391
• MGIID: 98497
• Length: 533
• Species: Mus musculus
• Alignment Length: 535
• Identity: 157/535 - (29%)
• Similarity: 251/535 - (46%)
• Gaps: 56/535 - (10%)

  Fly     4 GTV----LLTALLALVGYLLMKW--RSTMRHWQDLGIPCEEPHILMGSMKGVRTARSFNEIWTSY 62
            ||:    ||.||||     |:||  .|.....:.|||...:|...:|::...|..     .|.|.
Mouse    13 GTIVTVTLLVALLA-----LLKWYSMSAFSRLEKLGIRHPKPSPFVGNLMFFRQG-----FWESQ 67

  Fly    63 YNKFRGSGPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLSGQLFLLDGQK 127
            .......||..|:|..||..|.:.|..:.||:|::.|:.|::| .....|...::..:.||..::
Mouse    68 LELRERYGPLCGYYLGRRMHVVISEPDMIKQVLVENFSNFSNR-MASGLEPKMVADSVLLLRDRR 131

  Fly   128 WRTMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVRELLARFTTDVIGTCAFG 192
            |..:|..|.|:|:..|:..|.|.:.:..........:..|......::.....:|.||:.:.|||
Mouse   132 WEEVRGALMSSFSPEKLDEMTPLISQACELLVAHLKRYAASRDAFNIQRCYCCYTIDVVASVAFG 196

  Fly   193 IECSSLKDPDAEFREMGRRSLTEQRLGPVGIGFVNSFPN----LARRLHMKMTAEPIERFFMRIV 253
            .:..|...|:..|.:..||:.|.....|: :..:.|||:    |||.|..| ..:.:..||..::
Mouse   197 TQVDSQNSPEDPFVQHCRRASTFCIPRPL-LVLILSFPSIMVPLARILPNK-NRDELNGFFNTLI 259

  Fly   254 RETVAFREQN--NIRRNDFMDQLIDLKNKPLMVSQSG-----ESVN------------------- 292
            |..:|.|:|.  ..||.||:..::|.::....|...|     ||::
Mouse   260 RNVIALRDQQAAEERRRDFLQMVLDAQHSMNSVGVEGFDMVPESLSSSECTKEPPQRCHPTSTSK 324

  Fly   293 -LTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCNGELNYESMKD 356
             .|::||..|||:|..||.|..:.|:.|..|.||.:.|.|.|:.||....:.| :....|.|:::
Mouse   325 PFTVDEIVGQAFLFLIAGHEVITNTLSFITYLLATHPDCQERLLKEVDLFMGK-HPAPEYHSLQE 388

  Fly   357 -LVYLDQVVSETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNT 420
             |.|||.|:|||||:|.......||..:|.||.|..   |..|..:.|..||:|.|.:.:.||.|
Mouse   389 GLPYLDMVISETLRMYPPAFRFTREAAQDCEVLGQR---IPAGTVLEIAVGALHHDPEHWPNPET 450

  Fly   421 FNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSVCEKTTIPMTYN 485
            |:|:.|:.|...:|....:||||.|||:|:|:|.|.:..::.:..::..|:|....:|.:|:...
Mouse   451 FDPERFTAEARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRFEASPETQVPLQLE 515

  Fly   486 KEMFLIASNSGIYLK 500
            .:..|...| |:|:|
Mouse   516 SKSALGPKN-GVYIK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	CYP6-like	68..498	CDD:410679	135/461 (29%)
Tbxas1	NP_035669.3	cytochrome_P450	74..527	CDD:477761	135/460 (29%)