Protein Alignment Cyp6a21 and cyp-13A7

DIOPT Version :10

• Sequence 1: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0288232
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_496114.1
• Gene: cyp-13A7 / 188362
• WormBaseID: WBGene00000372
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 538
• Identity: 135/538 - (25%)
• Similarity: 240/538 - (44%)
• Gaps: 97/538 - (18%)

  Fly     1 MSVGTVLLTAL-LALVGYLLMKWRSTMRHW--QDLGIP----------CEEPHILMGSMKGVRTA 52
            ||...::..|: :.::.|.|..|...:|..  ...|:|          .|.|    |::|
 Worm     1 MSFSILIAIAIFVGIISYYLWIWSFWIRKGVKGPRGLPFLGVIHKFTNYENP----GALK----- 56

  Fly    53 RSFNEIWTSYYNKFRGSGPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLS 117
              |:| ||..|      ||..|........:.:.:.....::.:|:|:.|..|. ....:.||..
 Worm    57 --FSE-WTKKY------GPVYGITEGVEKTLVISDPEFVHEVFVKQFDNFYGRK-LTAIQGDPNK 111

  Fly   118 GQ---LFLLDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVRELLA 179
            .:   |....|.:|:.:|...|.||::..::.:..||.:...|......:..|:...:::.|...
 Worm   112 NKRVPLVAAQGHRWKRLRTLASPTFSNKSLRKIMGTVEESVTELVRSLEKASAEGKTLDMLEYYQ 176

  Fly   180 RFTTDVIGTCAFGIECSSL-KDPDAE-----FREMGRRSLTEQRLGP-VGIGFVN---SFPNLAR 234
            .||.|:||..|.|.|.|.: ::|..:     |:|..........:.| |||...|   .||:|
 Worm   177 EFTMDIIGKMAMGQEKSLMFRNPMLDKVKTIFKEGRNNVFMISGIFPFVGIALRNIFAKFPSL-- 239

  Fly   235 RLHMKMTAEPIERFFMRIVRETVAFRE-------QNNIRRNDFMDQLID---------------- 276
                 ..|..|:....:.:.:.:..||       :.:....||:|..:|
 Worm   240 -----QMATDIQSILEKALNKRLEQREADEKAGIEPSGEPQDFIDLFLDARSTVDFFEGEAEQDF 299

  Fly   277 LKNKPLMVSQSGESVNLTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEV 341
            .|::.|.|.:     :||.:||..|.|||..||::|::.::.::.|.||.:.:||.:::   :||
 Worm   300 AKSEVLKVDK-----HLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQ---EEV 356

  Fly   342 IEKC-NGELNYESMKDLVYLDQVVSETLRLYTVLPVL-NRECLEDYEVPGHPKYVIKKGMPVLIP 404
            ..:| :.|:.::.:..|.||:.||.|.||||.:..:: ||:||:...|.|   ..|:.|..:.:.
 Worm   357 DRECPDPEVTFDQLSKLKYLECVVKEALRLYPLASLVHNRKCLKTTNVLG---MEIEAGTNINVD 418

  Fly   405 CGAMHRDEKLYANPNTFNPDNFSPERVKERDSV-----EWLPFGDGPRNCIGMRFGQMQARIGLA 464
            ..::|.|.|::.:    :.:.|.|||.:..|.:     .:||||.|||.|||||...|:.::.|.
 Worm   419 TWSLHHDPKVWGD----DVNEFKPERWESGDELFFAKGGYLPFGMGPRICIGMRLAMMEMKMLLT 479

  Fly   465 LLIKDFKFSVCEKTTIPM 482
            .::|::.|....:|.||:
 Worm   480 NILKNYTFETTPETVIPL 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	CYP6-like	68..498	CDD:410679	117/458 (26%)
cyp-13A7	NP_496114.1	CYP3A-like	63..507	CDD:410678	118/464 (25%)