Protein Alignment Cyp6a21 and cyp-25A4

DIOPT Version :9

• Sequence 1: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0033981
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_497779.1
• Gene: cyp-25A4 / 183248
• WormBaseID: WBGene00007967
• Length: 501
• Species: Caenorhabditis elegans
• Alignment Length: 516
• Identity: 142/516 - (27%)
• Similarity: 241/516 - (46%)
• Gaps: 74/516 - (14%)

  Fly     3 VGTVLLTALLALVGYLLMKWRSTMRHWQDLGIPCEEPHILMGSMKGV--RTAR-SFNEI--W-TS 61
            :.|:..| ::..:.|.:.:..:..:....:|||....|.|.|::..:  |.:| .:|:.  | .:
 Worm     6 ISTIFFT-IITFISYSIWRRHAIFKLRSSIGIPGPPVHWLWGNLNIIKDRVSRLGYNDTTQWHPT 69

  Fly    62 YYNKFRGSGPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRG----FFHNPEDDPLSGQLFL 122
            .:.|:   ||..|.|...:..:.|.|....|:|.|:.|:.|:||.    |..|..:..|....:
 Worm    70 LHTKY---GPIFGLYCGTQLHITVSEEEDIKEIFIQNFSNFSDRMTPDIFGMNQLNQSLLQNTY- 130

  Fly   123 LDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVRELLARFTTDVIG 187
              ...|:..|:.::..|::||||.|..|:|...:.|.:|..:..:.....::.|.....:.|:||
 Worm   131 --ATGWKHTRSAIAPIFSTGKMKAMHETLVSKIDIFLEVLKEKSSSGQKWDIFENFQSLSLDIIG 193

  Fly   188 TCAFGIECSSLKDPDAEFREMGRR-----SLTEQRLGPVGI---------GFVNSFPNLARRLHM 238
            .|||.|:.:..:|....|....|:     .|.:..:.||.:         .|:..|.:|:
 Worm   194 KCAFAIDSNCQRDRTDLFYVQARKFVGAVDLKKSWILPVSLILPELSWLWRFLYKFSDLS----- 253

  Fly   239 KMTAEPIERFFMRIVRETVAFREQNNIRRNDFMDQLIDLKNKPLMVSQSGESV-NLTIEEIAAQA 302
              .||      :.:|:..|...::.  |..:..:...||.|  |::.:  |:: .:|..|:....
 Worm   254 --AAE------LPLVKGLVDLYDRR--RAGEGGNDSTDLLN--LLIRR--ETIGKMTQREVIENC 304

  Fly   303 FVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCNGELNYESMKDLVYLDQVVSET 367
            |.|..||:||:||.|.|:.|.||:...:|.::.:|.::..|  |..|||:|:.::.|||.|..|:
 Worm   305 FAFLIAGYETTSTAMMFSAYLLAEYPIVQQKLYEEIKKTKE--NAGLNYDSIHNMKYLDCVYKES 367

  Fly   368 LRLY-TVLPVLNRECLEDYEVPG--HPKYVIKKGMPVLIPCGAMHRDEKLYANP-NTFNPDNFSP 428
            ||.| ......||.||.|..:.|  :|:....|..|..|     ||      || |..:||.|.|
 Worm   368 LRFYPPTTHFTNRVCLNDMTIRGQIYPEDSTLKVQPYTI-----HR------NPANWESPDEFQP 421

  Fly   429 ERV----KERDSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSVC--EKTTIPMT 483
            ||.    ::..|::|:|||.|||.|:||||.:|:.:..:|.|:..|:.|:.  :...||.|
 Worm   422 ERFENWEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIAKLLDTFELSLVPGDPPMIPET 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	p450	35..499	CDD:278495	137/484 (28%)
cyp-25A4	NP_497779.1	p450	37..489	CDD:278495	137/484 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	208	1.000	Domainoid score	I1665
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I2346
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	O	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.880