Protein Alignment Cyp6a21 and cyp-25A1

DIOPT Version :10

• Sequence 1: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0288232
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 529
• Identity: 139/529 - (26%)
• Similarity: 244/529 - (46%)
• Gaps: 83/529 - (15%)

  Fly     7 LLTALLALVGYLLMKWRSTMRHWQDLGIPCEEPHILMGSMKGVRTA------------RSFNEIW 59
            |:.::.....|:::..|...:..:.:|:...|||..:|::|  :||            |.|||:.
 Worm     9 LVISIFTFFIYIILARRERFKLREKIGLSGPEPHWFLGNLK--QTAERKEKLGYDDANRWFNELH 71

  Fly    60 TSYYNKFRGSGPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLSGQLFLLD 124
            ..|...|       |.|:..:..:.:......|::.||.|:.|:||......|.:.|:..|.:..
 Worm    72 EQYGETF-------GIYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPSIYEANQLTASLLMNS 129

  Fly   125 -GQKWRTMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVRELLARFTTDVIGT 188
             ...|:..|:.::..|::||||.|..|:....:.|.|:..:..:.....::.:.....|.||||.
 Worm   130 YSSGWKHTRSAIAPIFSTGKMKAMQETINSKVDLFLDILREKASSGQKWDIYDDFQGLTLDVIGK 194

  Fly   189 CAFGIECSSLKDPDAEFREMGRRSLTEQRLGPVGIGFVNS---FPNLARRLHMKMTAEPI----- 245
            |||.|:.:..:|.:..|                   :||:   ..|:..| |.|:.|..:
 Worm   195 CAFAIDSNCQRDRNDVF-------------------YVNAKKYISNIDIR-HSKIIAASVLLPEL 239

  Fly   246 ERFFMRIVRET-VAFRE------QNNI---RRNDFMDQLIDLKNKPLMVSQSGESVNLTIEEIAA 300
            ..|:..:.:.| :|..|      .:|:   ||.......:||. |.|:..:..:|..:|.:|:..
 Worm   240 STFWKALYKYTPLADAEIPLVEGLSNVYERRRGGEGSDSVDLL-KLLLNREDDKSKPMTKQEVIE 303

  Fly   301 QAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCNGELNYESMKDLVYLDQVVS 365
            ..|.|..||:||:||.|.:..|.|::..::|.::.:|..|..|  ||.|.|:|:.::.|||.|..
 Worm   304 NCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEAKE--NGGLTYDSIHNMKYLDCVYK 366

  Fly   366 ETLRLY-TVLPVLNRECLEDYEVPG--HPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFS 427
            ||||.| .|:..:.|.|.||..:.|  :||..|...:|     ..:||:.:.:.:|..|:|:.|
 Worm   367 ETLRFYPPVIHFIRRLCREDITIRGQFYPKGAIVVCLP-----HTVHRNPENWDSPEEFHPERF- 425

  Fly   428 PERVKER-DSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSVCEKTTIPMTYNKEMFLI 491
             |..:|: .|::|:|||.|||.|:||||.:|:.:..:..|:..|:..         .:..|..||
 Worm   426 -ENWEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELK---------QFEGEADLI 480

  Fly   492 ASNSGIYLK 500
            ...:|:.::
 Worm   481 PDCNGVIMR 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	CYP6-like	68..498	CDD:410679	122/452 (27%)
cyp-25A1	NP_497775.3	CYP3A-like	73..495	CDD:410678	124/463 (27%)