DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Cyp6a21 and Cyp4f13

DIOPT Version :9

Sequence 1:NP_611003.2 Gene:Cyp6a21 / 36665 FlyBaseID:FBgn0033981 Length:504 Species:Drosophila melanogaster
Sequence 2:NP_570952.1 Gene:Cyp4f13 / 170716 MGIID:2158641 Length:523 Species:Mus musculus


Alignment Length:422 Identity:94/422 - (22%)
Similarity:191/422 - (45%) Gaps:72/422 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   116 LSGQLFLLDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVF---GQNVAKSPV--VEVR 175
            |...|.:..|.||...|..|:..|....:|    :.||:.|:..::.   .|.:|....  :::.
Mouse   132 LGDGLLMSAGDKWSHHRRLLTPAFHFDILK----SYVKIFNKSVNIMHAKWQCLASKGTSRLDMF 192

  Fly   176 ELLARFTTDVIGTCAFGIECSSLKDPDAEFREMGRRSLTEQRLGPVGIGFVNSFPNLARRLHMK- 239
            |.::..|.|.:..|.|.:: |:.::.|:::                 |..:....:|..:.|.: 
Mouse   193 EHISLMTLDSLQKCIFSVD-SNCQESDSKY-----------------IAAILELSSLVVKRHRQP 239

  Fly   240 ---------MTAEP---------IERFFMRIVRET--------VAF-REQNNIRRNDFMDQLIDL 277
                     :||:.         :..|...:::|.        |.| :.:...:..||:|     
Mouse   240 FLYLDLLYYLTADGRRFRKACDLVHNFTDAVIKERRSTLNTQGVEFLKAKAKTKTLDFID----- 299

  Fly   278 KNKPLMVSQSGESVNLTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVI 342
               .|::::......|:.|:|.|:|..|...|.:|:::.:.:.||.||::.:.|.|.|:|.||::
Mouse   300 ---VLLMAEDEHGKGLSNEDIRAEADTFMFGGHDTTTSALSWILYNLARHPEYQERCRQEVQELL 361

  Fly   343 -EKCNGELNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVP-GHPKYVIKKGMPVLIPC 405
             ::.:.|:.::.:..|.:|...:.|:|||:..:.:::|.|.:|..:| |.   .|.||...:|..
Mouse   362 RDRDSEEIEWDDLAQLPFLTMCIKESLRLHPPVLLISRCCTQDVLLPDGR---AIPKGNICVISI 423

  Fly   406 GAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDF 470
            ..:|.:..::.:|..:||..|.||..::|..:.::||..|.|||||..|...:.::.|||.:..|
Mouse   424 FGVHHNPSVWPDPEVYNPFRFDPENPQKRSPLAFIPFSAGTRNCIGQTFAMSEIKVALALTLLRF 488

  Fly   471 KFSVCEKTTIPMTYNKEMFLIASNSGIYLKAE 502
            :....:|.    ...|...::.:..|::|:.|
Mouse   489 RILPDDKE----PRRKPELILRAEGGLWLRVE 516

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cyp6a21NP_611003.2 p450 35..499 CDD:278495 92/417 (22%)
Cyp4f13NP_570952.1 p450 52..513 CDD:278495 92/417 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100014
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.