Protein Alignment Cyp6a21 and Cyp3a13

DIOPT Version :10

• Sequence 1: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0288232
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Alignment Length: 520
• Identity: 156/520 - (30%)
• Similarity: 259/520 - (49%)
• Gaps: 67/520 - (12%)

  Fly     1 MSVGTVLLTALLALVGYLLMKWRSTMRH--WQDLGIPCEEPHILMGSM----KG-----VRTARS 54
            |....:|.|:|:.|..|      .|..|  ::.||||..:|...:|::    ||     ::..:.
Mouse     9 METWMLLATSLVLLYLY------GTHSHGIFKKLGIPGPKPLPFLGTILAYQKGFWECDIQCHKK 67

  Fly    55 FNEIWTSYYNKFRGSGPFAGFYWFRRPAVFVLETSLAKQILIKE-FNKFTDRGFFHNPEDDP--- 115
            :.::|              |.|..|:|.:.:.:..:.|.:|:|| ::.||:|..|     .|
Mouse    68 YGKMW--------------GLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRF-----GPVGI 113

  Fly   116 LSGQLFLLDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQN----VAKSPVVEVRE 176
            |...:.:.:.::|:.:|..||.|||||::|.|||    :.|:||||..:|    :.:.....:::
Mouse   114 LKKAISISENEEWKRIRALLSPTFTSGRLKEMFP----IINQFTDVLVRNMRQGLGEGKPTSMKD 174

  Fly   177 LLARFTTDVIGTCAFGIECSSLKDPDAEFREMGRRSLTEQRLGPVGIGFVNSFPNLA---RRLHM 238
            :...::.|||...:||:...||.:|...|.|..::.|......|:.:. |..||.|.   ..|::
Mouse   175 IFGAYSMDVITATSFGVNIDSLNNPQDPFVEKIKKLLKFDIFDPLFLS-VTLFPFLTPVFDALNV 238

  Fly   239 KMTAEPIERFFMRIVRETVAFR-EQNNIRRNDFMDQLIDLKNKPLMVSQSGESVNLTIEEIAAQA 302
            .:....:..||...|......| ::...:|.||:..:|:.:|.....|...    |:..||.||:
Mouse   239 SLFPRDVISFFTTSVERMKENRMKEKEKQRVDFLQLMINSQNYKTKESHKA----LSDVEIVAQS 299

  Fly   303 FVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCNGELNYESMKDLVYLDQVVSET 367
            .:|..||:||:|:.:.||||.||.:.|:|.:::.|....:.. .....|:::..:.|||.||:||
Mouse   300 VIFIFAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAALPN-KAPATYDTLLQMEYLDMVVNET 363

  Fly   368 LRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVK 432
            ||||.:...|.|.|..|.|:.|   ..|.||..|:||..|:|:|.|.:..|..|.|:.||.   |
Mouse   364 LRLYPIAGRLERVCKTDVEING---LFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSK---K 422

  Fly   433 ERDSVE---WLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSVCEKTTIPMTYNKEMFLIASN 494
            .:||:.   :||||.||||||||||..:..::.|..::::|....|::|.||:..:|:..|...|
Mouse   423 NQDSINPYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQPCKETEIPLKLSKQGLLQPEN 487

  Fly   495  494
            Mouse   488  487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	CYP6-like	68..498	CDD:410679	139/442 (31%)
Cyp3a13	NP_031845.1	CYP3A	67..492	CDD:410743	140/456 (31%)