Protein Alignment Cyp6a21 and LOC1280399

DIOPT Version :10

• Sequence 1: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0288232
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_320246.5
• Gene: LOC1280399 / 1280399
• VectorBaseID: AGAMI1_004131
• Length: 549
• Species: Anopheles gambiae
• Alignment Length: 554
• Identity: 184/554 - (33%)
• Similarity: 274/554 - (49%)
• Gaps: 72/554 - (12%)

  Fly     6 VLLTALLALVGYLLMKWRSTMR---HWQDLGIPCEEPHILMGS-----MKGVRTARSFNEIWTSY 62
            :.:..|..|||..:..:|...:   ::.|..||..:|....|:     ||.|.....|..::.::
Mosquito     3 ISVVTLALLVGLCVAVYRYVTKNYFYFADKPIPFMKPSFPFGNAGPILMKKVTLFEHFKNLYDAF 67

  Fly    63 YNKFRGSGPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDR---GFFHNPEDDP----LSGQL 120
            .|     ....|.:..|:|...|.:..|.|||.:|:|:.|.|.   |.....:::.    |...|
Mosquito    68 PN-----ARIHGTFNMRQPVYIVRDPELVKQITVKDFDYFVDHMTTGMEQTEDNNSNHLLLGNSL 127

  Fly   121 FLLDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPV-------VEVRELL 178
            ..|.|||||.||..||..||..||:.||..:........:.|.:...|:..       :|:::::
Mosquito   128 VSLRGQKWRDMRATLSPAFTGSKMRLMFALIADCGKSMVEHFREEDKKARAAGGTGYQLEMKDVM 192

  Fly   179 ARFTTDVIGTCAFGIECSSLKDPDAEFREMGRRSLTEQR-----LGPVGIGFVNSFPNLARRLHM 238
            .||..|||||.||||:..|.:||...|..|. ||:|.|.     |..:|..|.   |.|..||::
Mosquito   193 TRFANDVIGTAAFGIKVDSFRDPTNVFISMA-RSVTNQESLVKVLKMIGYTFA---PKLMTRLNI 253

  Fly   239 KMTAEPIERFFMRIVRETVAFREQNNIRRNDFMDQLIDLK---------NKPLMVSQSGESVNLT 294
            .......::||...:.||:..|::..|.|.|.::.|:..|         .:|...|::||.. .|
Mosquito   254 DFLTPEEDQFFRNTILETMRTRQEKGIFRPDMIELLMQAKKGSLKHQQAEEPRTDSETGEGF-AT 317

  Fly   295 IE----------------EIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIE 343
            :|                |:.||||:||.|||||.|.|:.|||||||.|:|||.|:.:|.::..:
Mosquito   318 VEESHVGRRAHDRVWTDTELIAQAFIFFFAGFETISWTISFALYELAVNEDIQARLYEEVRDAEQ 382

  Fly   344 KC-NGE-LNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPG--HPKYVIKKGMPVLIP 404
            .. .|: |.||.::.|.|||.|||||||.:.:..||||||:.:|:...  ..::.|:||..|.||
Mosquito   383 SLEEGKTLTYEQLQSLPYLDMVVSETLRRWPIATVLNRECVRNYQYDDGQGTRFTIEKGTLVFIP 447

  Fly   405 CGAMHRDEKLYANPNTFNPDNFSPERVKERDSVE---WLPFGDGPRNCIGMRFGQMQARIGLALL 466
            ...:|.|.|.:..|..|:|:.||   ...|::::   :||||.|||||||.||..|:|:..|..|
Mosquito   448 VVGIHFDPKYFPEPERFDPERFS---AANRNNIQPGTYLPFGAGPRNCIGSRFALMEAKAALYYL 509

  Fly   467 IKDFKFSVCEKTTIPMTYNKEMFLIASNSGIYLK 500
            :.:|:...|.||.||:...|.....|:..||:|:
Mosquito   510 LLNFRLVPCAKTQIPLKLKKSSTQFATEQGIWLE 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	CYP6-like	68..498	CDD:410679	167/480 (35%)
LOC1280399	XP_320246.5	None