Protein Alignment Cyp6a21 and Cyp4v3

DIOPT Version :10

• Sequence 1: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0288232
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_598730.1
• Gene: Cyp4v3 / 102294
• MGIID: 2142763
• Length: 525
• Species: Mus musculus
• Alignment Length: 552
• Identity: 141/552 - (25%)
• Similarity: 228/552 - (41%)
• Gaps: 113/552 - (20%)

  Fly     5 TVLLTALLALVGYLLMKWRSTMRHWQDL-GIP-CEEPHILMGS---MKGVRTARSFNEIWTSYYN 64
            |:|::....||.|        .|.||.: .|| ....:.|:|.   || ...|..|.:: ..|..
Mouse    28 TILISIFPMLVSY--------ARKWQQMRSIPSVARAYPLVGHALYMK-PNNAEFFQQL-IYYTE 82

  Fly    65 KFR---------GSGPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLSGQL 120
            :||         |..|....|  :...|.|:.|| :|||         |:.|.:......|...|
Mouse    83 EFRHLPIIKLWIGPVPLVALY--KAENVEVILTS-SKQI---------DKSFLYKFLQPWLGLGL 135

  Fly   121 FLLDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVRELLARFT--- 182
            ....|.||||.|..|:.||..    .:....:.|.||..::....:.|....|........|
Mouse   136 LTSTGSKWRTRRKMLTPTFHF----TILENFLDVMNEQANILVNKLEKHVNQEAFNCFFYITLCA 196

  Fly   183 TDVIGTCAFGIECSSLKDPDAEF-REMGRRS--------------------LTEQRLGPVGIGFV 226
            .|:|...|.|....:..:.|:|: |.:.|.|                    ..|.|....|:..:
Mouse   197 LDIICETAMGKNIGAQSNNDSEYVRTVYRMSDMIYRRMKMPWLWFDLWYLVFKEGRDHKRGLKCL 261

  Fly   227 NSFPN--LARRLHMKMTAE--------PIERFFMRIVRETVAFREQNNIRRNDFMDQLIDLKNKP 281
            ::|.|  :|.|:..:...|        ||                .:..:|..|:|.|:.:.::
Mouse   262 HTFTNNVIAERVKERKAEEDWTGAGRGPI----------------PSKNKRKAFLDLLLSVTDE- 309

  Fly   282 LMVSQSGESVNLTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCN 346
                   |...|:.|:|..:...|...|.:|::..:.::||.|..|.::|.:|.:|..||..:.:
Mouse   310 -------EGNRLSQEDIREEVDTFMFEGHDTTAAAINWSLYLLGTNPEVQRKVDQELDEVFGRSH 367

  Fly   347 GELNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRD 411
            ..:..|.:|.|.|||.|:.||||::..:|:..|...||.||.|   |.:.||...:|...|:|||
Mouse   368 RPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVGG---YKVTKGTEAIIIPYALHRD 429

  Fly   412 EKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSVCE 476
            .:.:.:|..|.|:.|.||..:.|....::||..|||||||.:|..|:.:..||.:::.|.....:
Mouse   430 PRYFPDPEEFRPERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILRQFWVESNQ 494

  Fly   477 KTTIPMTYNKEM-----FLIASNSGIYLKAER 503
            |       .:|:     .::..|:||::|.:|
Mouse   495 K-------REELGLAGDLILRPNNGIWIKLKR 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	CYP6-like	68..498	CDD:410679	119/468 (25%)
Cyp4v3	NP_598730.1	CYP4V	76..515	CDD:410773	123/489 (25%)