Protein Alignment Cyp6a20 and ERG11

DIOPT Version :9

• Sequence 1: NP_611002.3
• Gene: Cyp6a20 / 36664
• FlyBaseID: FBgn0033980
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_011871.1
• Gene: ERG11 / 856398
• SGDID: S000001049
• Length: 530
• Species: Saccharomyces cerevisiae
• Alignment Length: 533
• Identity: 118/533 - (22%)
• Similarity: 195/533 - (36%)
• Gaps: 111/533 - (20%)

  Fly     3 VMIVLLIGVITFVAWYVHQHFN--------YWKRRGIPHDEPKIPYGNTSELMKTVHFADIFKRT 59
            :.::::|..|..:.|.:.....        ||    ||.....:.||     ||...|.:..::.
Yeast    31 ISLIIIIPFIYNIVWQLLYSLRKDRPPLVFYW----IPWVGSAVVYG-----MKPYEFFEECQKK 86

  Fly    60 YNKLRNKTDGPFVGFYMYFKRMVVVTDIDFAKTVLIREFDKFHDRGVFHNERDD----------- 113
            |        |....|.:..:.|.|...            .|.|: .||:.:..|
Yeast    87 Y--------GDIFSFVLLGRVMTVYLG------------PKGHE-FVFNAKLADVSAEAAYAHLT 130

  Fly   114 -PLSANLVNIDGQKWKTLRQK--LTPTFTSGKMKTMFPTILTVGDELIRVF--------GETASA 167
             |:....|..|....:.:.||  :....|....|:..|.|   .:|:.:.|        .|..:.
Yeast   131 TPVFGKGVIYDCPNSRLMEQKKFVKGALTKEAFKSYVPLI---AEEVYKYFRDSKNFRLNERTTG 192

  Fly   168 DSDSMEITNVVARFTADVIGSCAFGLDCHSLSDPKAKF----VQMGTTAITERRHGKSMDLLLFG 228
            ..|.|.....:..|||   .....|.:..:..|....:    :..|.|.|.            |.
Yeast   193 TIDVMVTQPEMTIFTA---SRSLLGKEMRAKLDTDFAYLYSDLDKGFTPIN------------FV 242

  Fly   229 APELAAK-LRMKATVQE-VEDFYMNIIRDTVDYRVKNNVKRHDFVDMLIEMKLKFDNGDKENG-- 289
            .|.|..: .|.:...|: :...||::|::.   |..|:::..|.:|.|::      |...::|
Yeast   243 FPNLPLEHYRKRDHAQKAISGTYMSLIKER---RKNNDIQDRDLIDSLMK------NSTYKDGVK 298

  Fly   290 LTFNEIAAQAFIFFLAGFETSSTTMGFALYELACHQDIQDKLRTEINTVLKQHNGKLDYDSMREM 354
            :|..|||.......:.|..||:.|..:.|..||...|:|.:|..|...||.....:|.||.::||
Yeast   299 MTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKELTYDLLQEM 363

  Fly   355 TYLEKVIDETMRKRPVVGHLIRVATQHYQHTNPKYNIEKGTGVIVPTLAIHHDPEFYPEPEKFIP 419
            ..|.:.|.||:|....:..|.|...:.....|..|.|..|..|:|.....|...|::|...:|..
Yeast   364 PLLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNI 428

  Fly   420 ERFDEDQ----------------VQQRPACTFLPFGDGPRNCIGLRFGRMQVIVGMALLIHNFKF 468
            .|:::|.                :.:..:..:||||.|...|||..|...|:.|.|::.|...|:
Yeast   429 HRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTLKW 493

  Fly   469 EFHPTKTVVPLEY 481
            .:...|||.|.::
Yeast   494 HYPEGKTVPPPDF 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a20	NP_611002.3	p450	32..496	CDD:278495	112/496 (23%)
ERG11	NP_011871.1	CYP51-like	83..521	CDD:410668	106/472 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	103	1.000	Domainoid score	I1492
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1477
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960