DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a20 and CYP97A3

DIOPT Version :9

Sequence 1:	NP_611002.3	Gene:	Cyp6a20 / 36664	FlyBaseID:	FBgn0033980	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_564384.1	Gene:	CYP97A3 / 840067	AraportID:	AT1G31800	Length:	595	Species:	Arabidopsis thaliana

Alignment Length:	500	Identity:	116/500 - (23%)
Similarity:	216/500 - (43%)	Gaps:	65/500 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 GIPHDEPKIP--YGNTSELMKTVHFADIFK--RTYNKLRNKTDGPFVGFYMYFKRMVVVTDIDFA 90
            |...|.||:|  .|:...:.....|..:::  .||..:...|.||        |..::|:|...|
plant   105 GSDQDYPKVPEAKGSIQAVRNEAFFIPLYELFLTYGGIFRLTFGP--------KSFLIVSDPSIA 161

  Fly    91 KTVLIREFDKFHDRGVFHNERDDPLSANLVNIDGQKWKTLRQKLTPTFTSGKMKTMFPTILTVGD 155
            |.:| ::..|.:.:|:.....|..:...|:..||:.|:..|:.:.|......:..|........|
plant   162 KHIL-KDNAKAYSKGILAEILDFVMGKGLIPADGEIWRRRRRAIVPALHQKYVAAMISLFGEASD 225

  Fly   156 ELIRVFGETASADSDSMEITNVVARFTADVIGSCAFGLDCHSLSDPKAKFVQMGTTAITERRHGK 220
            .|.:.. :.|:...:.:|:.::.:|.|.|:||...|..|..||::... .::...|.:.|.....
plant   226 RLCQKL-DAAALKGEEVEMESLFSRLTLDIIGKAVFNYDFDSLTNDTG-VIEAVYTVLREAEDRS 288

  Fly   221 SMDLLLFGAP---ELAAKLRMKATVQEVEDFYMNIIRDTVDYRVKNNVKRHDFVDMLIEMKLKFD 282
            ...:.::..|   :::.:.|..||       .:.:|.||:|..:. ..||     |:.|.:|:|.
plant   289 VSPIPVWDIPIWKDISPRQRKVAT-------SLKLINDTLDDLIA-TCKR-----MVEEEELQFH 340

  Fly   283 -----------------NGDKENGLTFNEIAAQAFIFFLAGFETSSTTMGFALYELACHQDIQDK 330
                             :||   .::..::........:||.|||:..:.:..|.|.....:..|
plant   341 EEYMNERDPSILHFLLASGD---DVSSKQLRDDLMTMLIAGHETSAAVLTWTFYLLTTEPSVVAK 402

  Fly   331 LRTEINTVLKQHNGKLDYDSMREMTYLEKVIDETMRKRPVVGHLIRVATQHYQHTNPKYNIEKGT 395
            |:.|:::|:......:  ..|:::.|..:|::|::|..|....|||.:..:  ....:|.|::|.
plant   403 LQEEVDSVIGDRFPTI--QDMKKLKYTTRVMNESLRLYPQPPVLIRRSIDN--DILGEYPIKRGE 463

  Fly   396 GVIVPTLAIHHDPEFYPEPEKFIPERFDED-----QVQQRPACTFLPFGDGPRNCIGLRFGRMQV 455
            .:.:....:|..|..:.:.|||.|||:..|     :..|.  .::||||.|||.|||..|...:.
plant   464 DIFISVWNLHRSPLHWDDAEKFNPERWPLDGPNPNETNQN--FSYLPFGGGPRKCIGDMFASFEN 526

  Fly   456 IVGMALLIHNFKFEFHPTKTVVPLEYRTDDFLLSSKGGIHLKVTR 500
            :|.:|:||..|.|:..|....|.:   |....:.:..|:.|.||:
plant   527 VVAIAMLIRRFNFQIAPGAPPVKM---TTGATIHTTEGLKLTVTK 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a20	NP_611002.3	p450	32..496	CDD:278495	112/492 (23%)
CYP97A3	NP_564384.1	PLN02738	1..595	CDD:215393	116/499 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900