DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a20 and CYP72A13

DIOPT Version :9

Sequence 1:	NP_611002.3	Gene:	Cyp6a20 / 36664	FlyBaseID:	FBgn0033980	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_188084.1	Gene:	CYP72A13 / 820694	AraportID:	AT3G14660	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	534	Identity:	129/534 - (24%)
Similarity:	221/534 - (41%)	Gaps:	99/534 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAVMIVLLIGVITFVAWYVHQHF-----------NYWKRRGIPHDEPKIPYGNTSELMKTVHFAD 54
            ::|..|.:...:..|:|:|.:..           :|.:|:|:    ...||        |....|
plant     3 ISVASVTVSVAVVVVSWWVWRTLQRVWLKPKMLESYLRRQGL----AGTPY--------TPLVGD 55

  Fly    55 IFKRTYNKLR-------NKTDG------PFV---------GFYMYFKRMVVVTDIDFAKTVLIRE 97
            : ||.::.|.       |.||.      |:.         .|:.:|..:..:|.:|..:   |:|
plant    56 L-KRNFSMLAEARSKPINLTDDITPRIVPYPLQMLKTHGRTFFTWFGPIPTITIMDPEQ---IKE 116

  Fly    98 -FDKFHDRGVFHNERDDPL----SANLVNIDGQKWKTLRQKLTPTFTSGKMKTMFPTILTVGDEL 157
             |:|.:|   |......||    :|.||:.||.||...|:.:.|.|...|:|.|.|.......|:
plant   117 VFNKVYD---FQKAHTFPLGRLIAAGLVSYDGDKWTKHRRIINPAFHLEKIKNMVPAFHQSCSEI 178

  Fly   158 IRVFGE-----TASADSDSMEITNVVARFTADVIGSCAFG---LDCHSLSDPKAKFVQMGTTAIT 214
            :   ||     |....|..::|...:...|||||...|||   .:...:.:.:|:..|:...|..
plant   179 V---GEWDKLVTDKQSSCEVDIWPWLVSMTADVISRTAFGSSYKEGQRIFELQAELAQLIIQAFR 240

  Fly   215 ERRHGKSMDLLLFGAPELAAK--LRMKATVQEVEDFYMNIIRDTVDYRVKNNVKRHDFVDMLIEM 277
            :        .::.|......|  .||||..:|::.....|:...:..|........|.:.:|:|.
plant   241 K--------AIIPGYRYFPTKGNRRMKAAAREIKFILRGIVNKRLRAREAGEAPSDDLLGILLES 297

  Fly   278 KLKFDNGDKENGLTFNEIAAQAFIFFLAGFETSSTTMGFALYELACHQDIQDKLRTEINTVLKQH 342
            .|   ...|.||::..|:..:..:|:.||.||::..:.:.:..|:.|||.|.:.|.|:..|.  .
plant   298 NL---GQTKGNGMSTEELMEECKLFYFAGQETTTVLLVWTMVLLSQHQDWQARAREEVKQVF--G 357

  Fly   343 NGKLDYDSMREMTYLEKVIDETMRKRPVVGHLIRVATQHYQHTNPKYNIEKGTGVIVPTLAIHHD 407
            :.:.|.:.:.::..:..::.|.:|..|.|..|.|..  |.:.......:..|..:.:|.|.|..|
plant   358 DKEPDAEGLNQLKVMTMILYEVLRLYPPVVQLTRAI--HKEMQLGDLTLPGGVQISLPILLIQRD 420

  Fly   408 PEFY-PEPEKFIPERFDE-------DQVQQRPACTFLPFGDGPRNCIGLRFGRMQVIVGMALLIH 464
            .|.: .:..:|.|:||.:       :||      :|.||..|||.|||..|..::..:.|.|::.
plant   421 RELWGNDAGEFKPDRFKDGLSKATKNQV------SFFPFAWGPRICIGQNFALLEAKMAMTLILR 479

  Fly   465 NFKFEFHPTKTVVP 478
            .|.||..|:....|
plant   480 KFSFELSPSYVHAP 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a20	NP_611002.3	p450	32..496	CDD:278495	121/492 (25%)
CYP72A13	NP_188084.1	p450	24..512	CDD:299894	124/513 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900