Protein Alignment Cyp6a20 and cyp26a1

DIOPT Version :10

• Sequence 1: NP_611002.3
• Gene: Cyp6a20 / 36664
• FlyBaseID: FBgn0033980
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: XP_012822016.1
• Gene: cyp26a1 / 548901
• XenbaseID: XB-GENE-855583
• Length: 492
• Species: Xenopus tropicalis
• Alignment Length: 494
• Identity: 107/494 - (21%)
• Similarity: 194/494 - (39%)
• Gaps: 71/494 - (14%)

  Fly     1 MAVMIVLLIGVITFVAWYVHQHFNYWKRRGIPHDEPKIP-YGNTSEL-MKTVHFADIFKRTYNKL 63
            :|:.::||:........|.....:...|..:|.....:| :|.|.:: ::...|..:.:|.|.::
 Frog    14 LALPVLLLLTAAKLWEVYCLSRKDASCRNPLPPGTMGLPFFGETLQMVLQRRKFLQVKRRKYGRI 78

  Fly    64 RNKTDGPFVGFYMYFKRMVVVTDIDFAKTVLIREFDKFHDRGVFHNERDDPLSAN-------LVN 121
             .||       :::....|.||..:..:.:|:.|    |.....|    .|.|..       |.|
 Frog    79 -YKT-------HLFGSPTVRVTGAENVRQILLGE----HKLVSVH----WPASVRTILGAGCLSN 127

  Fly   122 IDGQKWKTLRQKLTPTFTSGKMKTMFPTILTVGDELIRVFGETASADSDSMEITNVVARFTADVI 186
            :...:.|..::.:...|:...:....|   .:.:||.|.......:|| .:.:...:.|....:.
 Frog   128 LHDSEHKYTKKVIMQAFSREALANYVP---LMEEELRRSVNLWLQSDS-CVLVYPAIKRLMFRIA 188

  Fly   187 GSCAFGLDCHSLSDPKAKFVQMGTTAITERRHGKSMDLLLFGAPELAAKLRMKATVQEVEDFYMN 251
            .....|.|...|...:.:.:......:|.......:|:...|   |...||.:           |
 Frog   189 MRLLLGCDPQRLGREQEETLLEAFEEMTRNLFSLPIDVPFSG---LYRGLRAR-----------N 239

  Fly   252 IIRDTVDYRVKNNVKR------HDFVDMLIEMKLKFDNGDKENGLTFNEIAAQAFIFF-----LA 305
            ||...::..:|..::|      .|.:.:||:...:  .|:..|.....|.|.:  :.|     .|
 Frog   240 IIHAQIEENIKEKLQREPDGQCRDALQLLIDHSRR--TGEPVNLQALKESATE--LLFGGHGTTA 300

  Fly   306 GFETSSTTMGFALYELACHQDIQDKLRTEINT--VLK---QHNGKLDYDSMREMTYLEKVIDETM 365
            ...||.||.      ||.|:|:.:|:|.|:.:  :|.   :...:|..:.::::.|...||.||:
 Frog   301 SAATSLTTF------LALHKDVLEKVRKELESQGLLSNKPEEKKELSIEVLQQLKYTSCVIKETL 359

  Fly   366 RKRPVVGHLIRVATQHYQHTNPKYNIEKGTGVIVPTLAIHHDPEFYPEPEKFIPERFDEDQVQQR 430
            |..|.|....|||.:.:....  |.|.||..||......|.:.|.:|:.::|.|:||........
 Frog   360 RLSPPVAGGFRVALKTFVLNG--YQIPKGWNVIYSIADTHGEAELFPDKDEFNPDRFLTPLPGDS 422

  Fly   431 PACTFLPFGDGPRNCIGLRFGRMQVIVGMALLIHNFKFE 469
            ....|:|||.|.|.|:|..|.::.:.|.:..|..|..:|
 Frog   423 SRFGFIPFGGGVRCCVGKEFAKILLKVFIVELCRNCDWE 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a20	NP_611002.3	CYP6-like	67..495	CDD:410679	94/426 (22%)
cyp26a1	XP_012822016.1	cytochrome_P450	55..485	CDD:477761	100/453 (22%)