Protein Alignment Cyp6a20 and Cyp4a1

DIOPT Version :10

• Sequence 1: NP_611002.3
• Gene: Cyp6a20 / 36664
• FlyBaseID: FBgn0033980
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_787031.1
• Gene: Cyp4a1 / 50549
• RGDID: 68945
• Length: 509
• Species: Rattus norvegicus
• Alignment Length: 551
• Identity: 140/551 - (25%)
• Similarity: 238/551 - (43%)
• Gaps: 113/551 - (20%)

  Fly     1 MAVMIVLLIGVITFVAWYVHQHFNYWKRRGIPHDEPKIPY------------GNTSELMKTV-HF 52
            :|.::.||:.::..|.:|:.:.   |..:.. ...|..|:            ....::|..| :|
  Rat    21 VASVLGLLLLLVKAVQFYLQRQ---WLLKAF-QQFPSPPFHWFFGHKQFQGDKELQQIMTCVENF 81

  Fly    53 ADIFKRTYNKLRNKTDGPFVGFYMYFKRMVVVTDIDFAKTVLIREFDKFHDRGVFHNERDDPLSA 117
            ...|.|               ::...|..::|.|.|:.|.:|.|...|.:  ||:.      |.|
  Rat    82 PSAFPR---------------WFWGSKAYLIVYDPDYMKVILGRSDPKAN--GVYR------LLA 123

  Fly   118 -----NLVNIDGQKWKTLRQKLTPTFTSGKMKTMFPTILTVGDE---LIRVFGETASADSDSMEI 174
                 .|:.::||.|...|:.|||.|....:|   |.:..:.|.   ::..:.:.|..|| |:||
  Rat   124 PWIGYGLLLLNGQPWFQHRRMLTPAFHYDILK---PYVKNMADSIRLMLDKWEQLAGQDS-SIEI 184

  Fly   175 TNVVARFTADVIGSCAFGLDCHSLSDPKAKFVQMGTTAITERRHGKSMDLL-------------- 225
            ...::..|.|.:..|||..:.....|...|........:.:..|.:..::.
  Rat   185 FQHISLMTLDTVMKCAFSHNGSVQVDGNYKSYIQAIGNLNDLFHSRVRNIFHQNDTIYNFSSNGH 249

  Fly   226 LFG-APELA-------AKLRMKATVQ---EVEDFYMNIIRDTVDYRVKNNVKRHDFVDMLIEMKL 279
            ||. |.:||       .||| |..:|   |:|             :||.. :|.||:|:|:..::
  Rat   250 LFNRACQLAHDHTDGVIKLR-KDQLQNAGELE-------------KVKKK-RRLDFLDILLLARM 299

  Fly   280 KFDNGDKENGLTFNEIAAQAFIFFLAGFETSSTTMGFALYELACHQDIQDKLRTEINTVLKQHNG 344
              :|||   .|:..::.|:...|...|.:|:::.:.:..|.||.|.:.|.:.|.|:.:||.. ..
  Rat   300 --ENGD---SLSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQQRCREEVQSVLGD-GS 358

  Fly   345 KLDYDSMREMTYLEKVIDETMRKRPVVGHLIRVATQHYQHTNPKYNIEKGTGVIVPTLAIHHDPE 409
            .:.:|.:.::.|....|.|.:|..|.|..::|..:......:.: ::.||..|.:....:||:|:
  Rat   359 SITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGR-SLPKGIQVTLSIYGLHHNPK 422

  Fly   410 FYPEPEKFIPERFDEDQVQQRPACTFLPFGDGPRNCIGLRF--GRMQVIVGMALLIHNFKFEF-- 470
            .:|.||.|.|.||..|  ..|.:.:||||..|.|||||.:|  ..|:|||.:.||    :||.
  Rat   423 VWPNPEVFDPSRFAPD--SPRHSHSFLPFSGGARNCIGKQFAMSEMKVIVALTLL----RFELLP 481

  Fly   471 HPTKTVVPLEYRTDDFLLSSKGGIHLKVTRV 501
            .|||..:||    ...:|.||.||:|.:.::
  Rat   482 DPTKVPIPL----PRLVLKSKNGIYLYLKKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a20	NP_611002.3	CYP6-like	67..495	CDD:410679	125/464 (27%)
Cyp4a1	NP_787031.1	CYP4B-like	71..504	CDD:410771	131/491 (27%)