Protein Alignment Cyp6a20 and Cyp26c1

DIOPT Version :10

• Sequence 1: NP_611002.3
• Gene: Cyp6a20 / 36664
• FlyBaseID: FBgn0033980
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: XP_217935.3
• Gene: Cyp26c1 / 308190
• RGDID: 1308843
• Length: 518
• Species: Rattus norvegicus
• Alignment Length: 503
• Identity: 99/503 - (19%)
• Similarity: 180/503 - (35%)
• Gaps: 123/503 - (24%)

  Fly    48 KTVHFADIFKRTYNKLRNKTDGPFVGFYMYFKRMVVVTDIDFAKTVLIREFDKFHDRGVFHNERD 112
            :|:|:. :....::..|.:..|.....::..:.::.|:..:..:|:|:.|......:.
  Rat    61 ETLHWL-VQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQW------- 117

  Fly   113 DPLSAN-------LVNIDGQKWKTLRQKLTPTFTSGKMKTMFPTILTVGDELIRVFGETASADSD 170
             |.||:       |:...|::.:..|:.|...|:...::...|.:    .|.:|
  Rat   118 -PQSAHILLGSHTLLGAVGERHRQRRKVLARVFSRPALEQFVPRL----QEALR----------- 166

  Fly   171 SMEITNVVARFTADVIGSCAFGLDCHSLSDPKAKFVQMGTTAITERRHGKSMDLLLFGAPELAAK 235
                        .:|...||       ...|.|  |.....|:|.|...:    :|.|..  ..:
  Rat   167 ------------REVRSWCA-------AQRPVA--VYQAAKALTFRMAAR----ILLGLQ--LDE 204

  Fly   236 LRMKATVQEVEDFYMNIIRDTVD---------YRVKNNVKRHDFVDMLIEMKLKFD--------- 282
            .|.....|..|....|:....:|         .|.::.:.:|  :|.:|..||:.:
  Rat   205 ARCTELAQTFERLVENLFSLPLDVPFSGLRKGIRARDQLYQH--LDEVIAEKLREELTAEPGDAL 267

  Fly   283 ----NGDKENG--LTFNEIAAQAF-IFFLAGFETSSTTMGFALYELACHQDIQDKLRTEIN---- 336
                |..:|.|  |:..|:...|. :.|.|.|.|:|.:....|. |..|.....|::.|::
  Rat   268 HLIINSARELGRELSVQELKELAVELLFAAFFTTASASTSLILL-LLQHPAAIAKIQQELSAQGL 331

  Fly   337 ----TVLKQHNGK---------LDYDSMREMTYLEKVIDETMRKRPVVGHLIRVATQHYQHTNPK 388
                :...:.:|.         |....:..:.|::.|:.|.:|..|.|....|.|.:.::...
  Rat   332 GSPCSCAPRASGSRPDCSCEPDLSLAVLGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDG-- 394

  Fly   389 YNIEKGTGVIV------PTLAIHHDPEFYPEPEKFIPERF---DEDQVQQRPACTFLPFGDGPRN 444
            |.|.||..|:.      .|.|::..|     ||.|.||||   .||.........::|||.|.|:
  Rat   395 YQIPKGWSVMYSIRDTHETAAVYRSP-----PEGFDPERFGVESEDARGSGGRFHYIPFGGGARS 454

  Fly   445 CIGLRFGRMQVIVGMALLIHNFKFEF----HPTKTVVPLEYRTDDFLL 488
            |:|....:..:.:....|:...::|.    .|....||:.:..|..||
  Rat   455 CLGQELAQAVLQLLAVELVRTARWELATPAFPVMQTVPIVHPVDGLLL 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a20	NP_611002.3	CYP6-like	67..495	CDD:410679	96/484 (20%)
Cyp26c1	XP_217935.3	cytochrome_P450	59..504	CDD:477761	99/503 (20%)