Protein Alignment Cyp6a20 and Cyp4f4

DIOPT Version :10

• Sequence 1: NP_611002.3
• Gene: Cyp6a20 / 36664
• FlyBaseID: FBgn0033980
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_775146.1
• Gene: Cyp4f4 / 286904
• RGDID: 708363
• Length: 522
• Species: Rattus norvegicus
• Alignment Length: 551
• Identity: 131/551 - (23%)
• Similarity: 236/551 - (42%)
• Gaps: 110/551 - (19%)

  Fly     4 MIVLLIGVI---------TFVAWYVHQHFNYWKRRGIPHDEPKIPYGN-----------TSELMK 48
            :::||||..         |::.:..:||.         .|.|:.|..|           |.:.:|
  Rat    20 LLLLLIGASWLLVRVLTQTYIFYRTYQHL---------CDFPQPPKWNWFLGHLGMITPTEQGLK 75

  Fly    49 TVHFADIFKRTYNKLRNKTDGPFVGFYMYFKRMVVVTDIDFAKTVLIREFDKFHDRGVFHNERDD 113
            .|   .....||.:......||.:.........|:.:.:..:.:|.::|.       :|::....
  Rat    76 QV---TKLVATYPQGFMTWLGPILPIITLCHPDVIRSVLSASASVALKEV-------IFYSFLKP 130

  Fly   114 PLSANLVNIDGQKWKTLRQKLTPTFTSGKMKTMFPTILTVGDELIRVFGET-----------ASA 167
            .|...|:..||.||...|:.|||.|....:|           ..:::|.::           ||.
  Rat   131 WLGDGLLLSDGDKWSCHRRMLTPAFHFNILK-----------PYVKIFNDSTNIMHAKWQDLASG 184

  Fly   168 DSDSMEITNVVARFTADVIGSCAFGLDCHSLSDPKAKFVQ--MGTTAITERR------HGKSMDL 224
            .|..:::...::..|.|.:..|.|..|.:....| ::::.  :..:|:..:|      |..|:..
  Rat   185 GSARLDMFKNISLMTLDSLQKCVFSFDSNCQEKP-SEYISAILELSALVAKRYQQLLLHTDSLYQ 248

  Fly   225 LLFGAPEL--AAKL-----------RMKATVQEVEDFYMNIIRDTVDYRVKNNVKRHDFVDMLIE 276
            |.......  |.||           |.:|...:.||..:         :.|...|..||:|:|:.
  Rat   249 LTHNGRRFHKACKLVHNFTDAVIQGRRRALPSQHEDDIL---------KAKARSKTLDFIDVLLL 304

  Fly   277 MKLKFDNGDKENGLTFNEIAAQAFIFFLAGFETSSTTMGFALYELACHQDIQDKLRTEINTVLK- 340
            .|   |...||  |:..:|.|:|..|...|.:|:::.:.:.||.||.|.:.|::.|.|:..:|:
  Rat   305 TK---DEDGKE--LSDEDIRAEADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVRELLRD 364

  Fly   341 QHNGKLDYDSMREMTYLEKVIDETMRKRPVVGHLIRVATQHYQHTNPKYNIEKGTGVIVPTLAIH 405
            :.:.::::|.:.::.:|...|.|::|..|.|..:.|..||.....:.:. |.||...|:...|.|
  Rat   365 RESTEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRRCTQDIVLPDGRV-IPKGVICIINIFATH 428

  Fly   406 HDPEFYPEPEKFIPERFDEDQVQQRPACTFLPFGDGPRNCIGLRFGRMQVIVGMALLIHNFKFEF 470
            |:|..:|:||.:.|.|||.:.::.|....|:||..|||||||..|...::.|.:||.:..|:
  Rat   429 HNPTVWPDPEVYDPFRFDPENIKDRSPLAFIPFSAGPRNCIGQTFAMNEMKVALALTLLRFR--- 490

  Fly   471 HPTKTVVPLE---YRTDDFLLSSKGGIHLKV 498
                 |:|.:   .|..:.:|.::||:.|:|
  Rat   491 -----VLPDDKEPRRKPELILRAEGGLWLRV 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a20	NP_611002.3	CYP6-like	67..495	CDD:410679	113/463 (24%)
Cyp4f4	NP_775146.1	CYP4F	74..515	CDD:410772	117/485 (24%)