Protein Alignment Cyp6a20 and Cyp17a1

DIOPT Version :10

• Sequence 1: NP_611002.3
• Gene: Cyp6a20 / 36664
• FlyBaseID: FBgn0033980
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_036885.2
• Gene: Cyp17a1 / 25146
• RGDID: 2456
• Length: 507
• Species: Rattus norvegicus
• Alignment Length: 520
• Identity: 120/520 - (23%)
• Similarity: 220/520 - (42%)
• Gaps: 94/520 - (18%)

  Fly     8 LIGVITFVAWYVHQHFNYW---KRRG--IPHDEPKIP-YGNTSELMKTVHF-ADIFKRTYNKLRN 65
            |:|::..:..|.     :|   |..|  :|...|.:| .|:...|.:..|. .:.|     ||:.
  Rat     4 LVGLLLLILAYF-----FWVKSKTPGAKLPRSLPSLPLVGSLPFLPRRGHMHVNFF-----KLQE 58

  Fly    66 KTDGPFVGFYMYFKRMVVVTDIDFAKTVLIREFDKFHDRGVFHNERDDPLSANLVNIDGQ----- 125
            |. ||.....:.....|::.....|:.|||::..:|       :.|...::.:|::..|:
  Rat    59 KY-GPIYSLRLGTTTTVIIGHYQLAREVLIKKGKEF-------SGRPQMVTQSLLSDQGKGVAFA 115

  Fly   126 ----KWKTLRQKLTPTFTSGKMKTMFPTILTVGDELIRVFGETASA--------DSDSMEITNVV 178
                .|...|:.:..||          ::...|.:|.::..:.|.:        |.:|::::..:
  Rat   116 DAGSSWHLHRKLVFSTF----------SLFKDGQKLEKLICQEAKSLCDMMLAHDKESIDLSTPI 170

  Fly   179 ARFTADVIGSCAFGLDCHSLSDPKAKFVQMGTTAITERRHGKSMD-----LLLFGAPELA----- 233
            .....::|.:..|.:. :...|||...::..|..|.:....:::.     |.:|....|.
  Rat   171 FMSVTNIICAICFNIS-YEKKDPKLTAIKTFTEGIVDATGDRNLVDIFPWLTIFPNKGLEVIKGY 234

  Fly   234 AKLRMKATVQEVEDFYMNIIRDTVDYRVKNNVKRHDFVDMLIEMKLKFDNGDKENG-----LTFN 293
            ||:|     .||........|:..|.:..:::     .|:||:.|:..||.:...|     .:..
  Rat   235 AKVR-----NEVLTGIFEKCREKFDSQSISSL-----TDILIQAKMNSDNNNSCEGRDPDVFSDR 289

  Fly   294 EIAAQAFIFFLAGFETSSTTMGFALYELACHQDIQDKLRTEINTVLKQHNG---KLDYDSMREMT 355
            .|.|.....|.||.||::|.:.:.|..|..:.:::.|::.||:    |:.|   ...::....:.
  Rat   290 HILATVGDIFGAGIETTTTVLKWILAFLVHNPEVKKKIQKEID----QYVGFSRTPTFNDRSHLL 350

  Fly   356 YLEKVIDETMRKRPVVGHLIRVATQHYQHTNP---KYNIEKGTGVIVPTLAIHHDPEFYPEPEKF 417
            .||..|.|.:|.|||...||    .|..:.:.   ::.:.|.|.|:|...|:|||...:.:|::|
  Rat   351 MLEATIREVLRIRPVAPMLI----PHKANVDSSIGEFTVPKDTHVVVNLWALHHDENEWDQPDQF 411

  Fly   418 IPERFDEDQVQQ--RPACTFLPFGDGPRNCIGLRFGRMQVIVGMALLIHNFKFEFHPTKTVVPLE 480
            :||||.:.....  .|..::||||.|||:|||....|.::.|..|||:..|..:....|.:..||
  Rat   412 MPERFLDPTGSHLITPTQSYLPFGAGPRSCIGEALARQELFVFTALLLQRFDLDVSDDKQLPRLE 476

  Fly   481  480
              Rat   477  476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a20	NP_611002.3	CYP6-like	67..495	CDD:410679	104/454 (23%)
Cyp17a1	NP_036885.2	CYP17A1	60..490	CDD:410766	104/454 (23%)