Protein Alignment Cyp6a20 and cyp-13A8

DIOPT Version :10

• Sequence 1: NP_611002.3
• Gene: Cyp6a20 / 36664
• FlyBaseID: FBgn0033980
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_496115.1
• Gene: cyp-13A8 / 188358
• WormBaseID: WBGene00011674
• Length: 509
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 134/545 - (24%)
• Similarity: 245/545 - (44%)
• Gaps: 102/545 - (18%)

  Fly     6 VLLIGVITFVAWYVHQHFNYWKRRGIPHDEPKIPYGNTSELMKTVHFADIFKRTYNKLR-NKTDG 69
            ::||.::|:..|    |:.:|||||:|.......:|....:::     |.|...|...: .|..|
 Worm     5 LILISIVTYYFW----HWTFWKRRGLPGPWGVPIFGKAGAMLE-----DSFPPGYTLQKWTKEYG 60

  Fly    70 PFVGFYMYFKRMVVVTDIDFAKTVLIREFDKFHDRGVFHN----ERDDPLSANLVNIDGQKWKTL 130
            ...||....::::|::|.|..:.:|::::|.|:.|.  ||    :.|.....::|...|.:||.|
 Worm    61 KIYGFTEGMQKVMVISDPDLVQEILVKQYDNFYGRK--HNPVQGDPDKDKDIHIVGAQGFRWKRL 123

  Fly   131 RQKLTPTFTSGKMKTMFPTILTVGDELIRVFGETASADSDSMEITNV---VARFTADVIGSCAFG 192
            |....|.|::|.:|.:..|:.....||::...|    :|::.:..|:   ...:|.|||...|.|
 Worm   124 RTITAPAFSNGSIKKVLTTMEDSTQELMKKLRE----ESENGKAVNMHLFYQEYTFDVISRVAMG 184

  Fly   193 L-DCHSLSDPKAKFVQMGTTAITERRHGKSMDLLLFGAPELAAKLRMKATVQEVEDF-------Y 249
            . |.....:|..|.|:    ...|  |.:....:..|....|... :|....:|..|       .
 Worm   185 QPDSQMFKNPLLKDVK----GFFE--HNRWQIWMFSGGFPFAVSF-LKWLFIKVGKFGAGPFIVV 242

  Fly   250 MNIIRDTVDYRV--KNNVKRH--------DFVDMLIEMKLKFDNGDKENG------------LTF 292
            ...:.|.|..|:  :...|:|        |::||.:..:.:.::..:.|.            ||.
 Worm   243 QKSVTDAVMSRIAQREADKKHGVEPGEAADYIDMFLNARAEVEHFGESNDEFHKSSSYNNRQLTT 307

  Fly   293 NEIAAQAFIFFLAGFETSSTTMGFALYELACHQDIQDKLRTEINTVLKQHNGKLDYDSMREMTYL 357
            .||.:|.|:|.:|||:|::.::.:..|.||.:..||.||:.|::.  :..|.::.:|.:.::.|:
 Worm   308 QEIISQCFVFLVAGFDTTAISLSYVTYFLALNPKIQSKLQDEVDK--ECPNDEITFDQLSKLKYM 370

  Fly   358 EKVIDETMRKRP--------------VVGHLIRVATQHYQHTNPKYNIEKGTGVIVPTLAIHHDP 408
            :.||.|::|..|              |:|..|               :|.|..|::.|..:|||.
 Worm   371 DNVIKESLRLFPFASFANSRRCMRNTVIGEQI---------------VEAGVDVMIDTWTLHHDK 420

  Fly   409 EFY-PEPEKFIPERFDEDQVQQRPACTFLPFGDGPRNCIGLRFGRMQVIVGMALLIHNFKFEFHP 472
            ..: .:.|:|.|||:|.....|:   .:|.||.|||.|:|:||..::....::.::..:.||.:
 Worm   421 NVWGNDVEEFKPERWDSPLTPQQ---AYLSFGAGPRVCLGMRFALLEQKGLLSHILKKYTFETN- 481

  Fly   473 TKTVVPLEY------RTDDFLLSSK 491
            .||.:|::.      |.::..||.|
 Worm   482 AKTQLPIKLVGRATARPENLFLSLK 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a20	NP_611002.3	CYP6-like	67..495	CDD:410679	118/483 (24%)
cyp-13A8	NP_496115.1	CYP3A-like	58..500	CDD:410678	115/475 (24%)