Protein Alignment Cyp6a20 and cyp-13A12

DIOPT Version :10

• Sequence 1: NP_611002.3
• Gene: Cyp6a20 / 36664
• FlyBaseID: FBgn0033980
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 528
• Identity: 144/528 - (27%)
• Similarity: 259/528 - (49%)
• Gaps: 80/528 - (15%)

  Fly     1 MAV----MIVLLIGVITFVAWYVHQHFNYWKRRGI--PHDEPKIPYGNTSELMKTVH--FADI-- 55
            ||:    ::..:|||::|..|    .::|||||||  |...|.:  |:..|::.:.:  :..:
 Worm     1 MAIIFLAILTSIIGVLSFYLW----TWSYWKRRGIAGPSGYPIL--GSALEMLSSENPPYLQLKE 59

  Fly    56 FKRTYNKLRNKTDGPFVGFYMYFKRMVVVTDIDFAKTVLIREFDKFHDRGV--FHNERDDPLSAN 118
            :.:.|.|:...|:|        ..|.:|::|.|..:.|.::::|.|..|.:  ...:.:.....|
 Worm    60 WTKQYGKVYGITEG--------LSRTLVISDPDLVQEVFVKQYDNFFGRKLNPIQGDPNKDKRVN 116

  Fly   119 LVNIDGQKWKTLRQKLTPTFTSGKMKTMFPTILTVGDELIRVFGETASADSDSMEITNVVARFTA 183
            |.:..|.:||.||...:|||::..::.:..|:.....||:|.. |..:.....:::.:....||.
 Worm   117 LFSSQGHRWKRLRTISSPTFSNNSLRKLKTTVEECAVELLRHI-EQHTDGGQPIDLLDFYQEFTL 180

  Fly   184 DVIGSCAFG-LDCHSLSDPKAKFVQMGTTAITERRHGKSMDLLLFG--APELAAKLRMK--ATVQ 243
            ||||..|.| .|.....:|...:|:   ....|.|.|    |.|.|  ||.:...|||.  :...
 Worm   181 DVIGRIAMGQTDSQMFKNPLLPYVR---AVFGEPRKG----LFLSGSLAPWIGPILRMVMFSLPN 238

  Fly   244 EVEDFYMNIIRDT---VDYRVKNNV----------KRHDFVDMLIEMKLKFDNGDKENG------ 289
            .|::..:::||.|   |:.|||..:          :..||:|:.::  .|.|:.:.||.
 Worm   239 IVKNPAVHVIRHTSNAVEQRVKLRMADEKAGIDPGEPQDFIDLFLD--AKSDDVELENNEDFTKA 301

  Fly   290 -------LTFNEIAAQAFIFFLAGFETSSTTMGFALYELACHQDIQDKLRTEINTVLKQHNGKLD 347
                   ||..||..|.|:|.:|||:|::.::.::.:.||.|..:|.||:.||:.  :..:.::.
 Worm   302 GVKVTRQLTTEEIVGQCFVFLIAGFDTTALSLSYSSFLLATHPKVQKKLQEEIDR--ECADPEVT 364

  Fly   348 YDSMREMTYLEKVIDETMRKRPVVGHLI--RVATQHYQHTNPKYNIEKGTGVIVPTLAIHHDPEF 410
            :|.:.::.|:|.||.||:|..| :|.|.  |...:..:..|  |.|::||.::..|..:|.|...
 Worm   365 FDQLSKLKYMECVIKETLRMYP-LGALANSRCCMRATKIGN--YEIDEGTNILCDTWTLHSDKSI 426

  Fly   411 YPE-PEKFIPERFD--EDQVQQRPACTFLPFGDGPRNCIGLRFGRMQVIVGMALLIHNFKFEFHP 472
            :.| .|:|.|||::  ::...|:..  ::|||.|||.|||:|...|:..:.::.::..:..|. .
 Worm   427 WGEDAEEFKPERWESGDEHFYQKGG--YIPFGLGPRQCIGMRLAYMEEKLLLSHILRKYTLEV-C 488

  Fly   473 TKTVVPLE 480
            .||.:||:
 Worm   489 NKTQIPLK 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a20	NP_611002.3	CYP6-like	67..495	CDD:410679	124/452 (27%)
cyp-13A12	NP_499705.1	CYP3A-like	63..507	CDD:410678	126/460 (27%)