Protein Alignment Cyp6a20 and Cyp3a62

DIOPT Version :10

• Sequence 1: NP_611002.3
• Gene: Cyp6a20 / 36664
• FlyBaseID: FBgn0033980
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001019403.1
• Gene: Cyp3a62 / 170509
• RGDID: 1595919
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 530
• Identity: 179/530 - (33%)
• Similarity: 272/530 - (51%)
• Gaps: 78/530 - (14%)

  Fly     1 MAVMIVLLIGVITFVAWYVH---QHFNYWKRRGIPHDEPKIPY-GNTSELMKTVH-FADIFKRTY 60
            :|.::|||         |::   .|.|: |:.||...:| :|: ||   ::...| |.:..:..:
  Rat    15 LATILVLL---------YLYGTSTHGNF-KKLGISGPKP-LPFVGN---ILAYRHGFWEFDRHCH 65

  Fly    61 NKLRNKTDGPFVGFYMYFKRMVVVTDIDFAKTVLIRE-FDKFHDRGVFHNERDDP---LSANLVN 121
            .|.     |...|||...:.::.:||.|..||||::| :..|.:|..|     .|   |...:..
  Rat    66 KKY-----GDIWGFYEGRQPILAITDPDIIKTVLVKECYSTFTNRRSF-----GPAGILKKAITL 120

  Fly   122 IDGQKWKTLRQKLTPTFTSGKMKTMFPTILTVGDELIR-VFGETASADSDSMEITNVVARFTADV 185
            .:.::||.||..|:|||||||:|.|||.|....|.|:: |..|....:..:|:  ::...::.||
  Rat   121 SEDEEWKRLRTLLSPTFTSGKLKEMFPIINQYADLLVKNVKHEAEKGNPITMK--DIFGAYSMDV 183

  Fly   186 IGSCAFGLDCHSLSDPKAKFVQMGTTAITERRHGKSMDLLLFG---------------APELAAK 235
            |...:||::..||::|:..|||            |...||.|.               .|...|
  Rat   184 ITGTSFGVNVDSLNNPQNPFVQ------------KVKKLLKFNFLDPFFLSVILFPFLTPVFEA- 235

  Fly   236 LRMKATV--QEVEDFYMNIIRDTVDYRVKNNVK-RHDFVDMLIEMKLKFDNGDKEN--GLTFNEI 295
              ...||  ::|..|:...:....:.|::..|| |.||:.::|..:   .:||||:  |||..||
  Rat   236 --FDITVFPKDVMKFFRTSVERMKENRMQEKVKQRLDFLQLMINSQ---SSGDKESHQGLTDVEI 295

  Fly   296 AAQAFIFFLAGFETSSTTMGFALYELACHQDIQDKLRTEINTVLKQHNGKLDYDSMREMTYLEKV 360
            .||:..|..||:||:|:.:.||||.||.|.|:|.||:.||:..| .:...:.||.:.||.||:.|
  Rat   296 VAQSIFFIFAGYETTSSALSFALYLLATHPDLQKKLQDEIDAAL-PNKAPVTYDVLVEMEYLDMV 359

  Fly   361 IDETMRKRPVVGHLIRVATQHYQHTNPKYNIEKGTGVIVPTLAIHHDPEFYPEPEKFIPERFDED 425
            ::||:|..||.|.|.||..:..: .|..: |.|||.|:|||.|:|.||:.:||||:|.||||.:.
  Rat   360 LNETLRLFPVGGRLERVCKKDVE-INGVF-IPKGTVVMVPTFALHKDPKCWPEPEEFCPERFRKK 422

  Fly   426 QVQQRPACTFLPFGDGPRNCIGLRFGRMQVIVGMALLIHNFKFEFHPTKTVVPLEYRTDDFLLSS 490
            .........:||||:|||||||:||..|.:.:.:..::.||.|.. ..:|.:||:.|...|....
  Rat   423 NQDSINPYIYLPFGNGPRNCIGMRFALMNMKIALVRVLQNFSFGL-CKETQIPLKLRKKGFFQPE 486

  Fly   491 KGGIHLKVTR 500
            |..|...|:|
  Rat   487 KPIILRAVSR 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a20	NP_611002.3	CYP6-like	67..495	CDD:410679	159/452 (35%)
Cyp3a62	NP_001019403.1	CYP3A	67..492	CDD:410743	161/458 (35%)