Protein Alignment Cyp6a20 and Cyp4b1

DIOPT Version :10

• Sequence 1: NP_611002.3
• Gene: Cyp6a20 / 36664
• FlyBaseID: FBgn0033980
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_031849.1
• Gene: Cyp4b1 / 13120
• MGIID: 103225
• Length: 511
• Species: Mus musculus
• Alignment Length: 544
• Identity: 127/544 - (23%)
• Similarity: 231/544 - (42%)
• Gaps: 109/544 - (20%)

  Fly     2 AVMIVLLIGVITFVAWYVHQHFNYWKRRGIPHDEPKIP-------YGNTSELMKT------VHFA 53
            |.:::|::.|:..::.       .::|:.:.......|       :|:..|:.||      |.:.
Mouse    17 ASVVILMVTVLKLLSL-------LFRRQKLARALDSFPGPPKHWLFGHALEIQKTGGLDKVVTWT 74

  Fly    54 DIFKRTYNKLRNKTDGP-FVGFYMYFKRMVVVTDIDFAKTVLIREFDKFHDRGVFHNERDDPLSA 117
            :.|...:         | ::|.::.|   :.:.:.|:||.|        :.||       ||.:|
Mouse    75 EQFPYAH---------PLWLGQFIVF---LNIYEPDYAKAV--------YSRG-------DPKAA 112

  Fly   118 ------------NLVNIDGQKWKTLRQKLTPTFTSGKMKTMFPTILTVGDELIRVF---GETASA 167
                        .|:.::|.||...|:.|||.|....:|    ..:.:..|..||.   .|..::
Mouse   113 YVYDFFLQWIGKGLLVLEGPKWFQHRKLLTPGFHYDVLK----PYVAIFAESTRVMLDKWEKKAS 173

  Fly   168 DSDSMEITNVVARFTADVIGSCAFGLDCHSL--SDPKAKFVQMGTTAITERR------HGKSMDL 224
            ::.|.:|...|.....|.:..|.||.....|  ||..........|.:.::|      |.   |.
Mouse   174 ENKSFDIFCDVGHMALDTLMKCTFGKGDSGLSHSDNSYYLAVSDLTLLMQQRIDSFQYHN---DF 235

  Fly   225 LLFGAPELAAKLRMKATVQEVEDFYMNIIR-------DTVDYRVKNNVKRH-DFVDMLIEMKLKF 281
            :.:..|.....||   ..|...|...::||       |..:.: |...:|| ||:|:|:..:
Mouse   236 IYWLTPHGRRFLR---ACQIAHDHTDHVIRQRKAALQDEKEQK-KLQERRHLDFLDILLGAR--- 293

  Fly   282 DNGDKENGLTFN--EIAAQAFIFFLAGFETSSTTMGFALYELACHQDIQDKLRTEINTVLKQHNG 344
                .|:|:..:  ::.|:...|...|.:|:::.:.:.||.:|.:...|.:.|.|:..:|...:
Mouse   294 ----DESGIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPMHQQRCREEVREILGDRD- 353

  Fly   345 KLDYDSMREMTYLEKVIDETMRKRPVVGHLIRVATQHYQHTNPKYNIEKGTGVIVPTLAIHHDPE 409
            ...:|.:.:||||...:.|..|..|.|..:.|..::.....:.: ::..|:.:.:...|:|.:..
Mouse   354 SFQWDDLAQMTYLTMCMKECFRLYPPVPQVYRQLSKPVTFVDGR-SLPAGSLISLHIYALHRNSA 417

  Fly   410 FYPEPEKFIPERFDEDQVQQRPACTFLPFGDGPRNCIGLRF--GRMQVIVGMALLIHNFKFEFHP 472
            .:|:||.|.|.||..:.:..|....|:||..|||||||.:|  ..|:|:..:.||    :|||.|
Mouse   418 VWPDPEVFDPLRFSPENMTGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLL----RFEFSP 478

  Fly   473 TKTVVPLEYRTDDFLLSSKGGIHL 496
            ..:.:|:  :....:|.||.||||
Mouse   479 DPSKIPI--KVPQLILRSKNGIHL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a20	NP_611002.3	CYP6-like	67..495	CDD:410679	113/463 (24%)
Cyp4b1	NP_031849.1	CYP4B-like	67..501	CDD:410771	118/487 (24%)