Protein Alignment Cyp6a20 and Cyp3a13

DIOPT Version :10

• Sequence 1: NP_611002.3
• Gene: Cyp6a20 / 36664
• FlyBaseID: FBgn0033980
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Alignment Length: 518
• Identity: 163/518 - (31%)
• Similarity: 265/518 - (51%)
• Gaps: 53/518 - (10%)

  Fly     1 MAVMIVLLIGVITFVAWYVHQHFNYWKRRGIPHDEPKIPY-GNTSELMKTVHFADI-FKRTYNKL 63
            |...::|...::....:..|.| ..:|:.|||..:| :|: |......|.....|| ..:.|.|:
Mouse     9 METWMLLATSLVLLYLYGTHSH-GIFKKLGIPGPKP-LPFLGTILAYQKGFWECDIQCHKKYGKM 71

  Fly    64 RNKTDGPFVGFYMYFKRMVVVTDIDFAKTVLIRE-FDKFHDRGVFHNERDDPLS--ANLVNI-DG 124
            ....||.        :.::.:||.|..||||::| :..|.:|     .|..|:.  ...::| :.
Mouse    72 WGLYDGR--------QPVLAITDPDIIKTVLVKECYSTFTNR-----RRFGPVGILKKAISISEN 123

  Fly   125 QKWKTLRQKLTPTFTSGKMKTMFPTILTVGDELIRVFGETASADSDSMEITNVVARFTADVIGSC 189
            ::||.:|..|:||||||::|.|||.|....|.|:|...: ...:.....:.::...::.|||.:.
Mouse   124 EEWKRIRALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQ-GLGEGKPTSMKDIFGAYSMDVITAT 187

  Fly   190 AFGLDCHSLSDPKAKFVQMGTTAITERRHGK---------SMDLLLFGAPELAAKLRMKATVQEV 245
            :||::..||::|:..||:.....:      |         |:.|..|..|...| |.:....::|
Mouse   188 SFGVNIDSLNNPQDPFVEKIKKLL------KFDIFDPLFLSVTLFPFLTPVFDA-LNVSLFPRDV 245

  Fly   246 EDFYMNIIRDTVDYRVKNNVK-RHDFVDMLIEMKLKFDNGDKENGLTFNEIAAQAFIFFLAGFET 309
            ..|:...:....:.|:|...| |.||:.::|..: .:...:....|:..||.||:.||..||:||
Mouse   246 ISFFTTSVERMKENRMKEKEKQRVDFLQLMINSQ-NYKTKESHKALSDVEIVAQSVIFIFAGYET 309

  Fly   310 SSTTMGFALYELACHQDIQDKLRTEINTVLKQHNGKLDYDSMREMTYLEKVIDETMRKRPVVGHL 374
            :|:.:.||||.||.|.|:|.||:.||:..| .:.....||::.:|.||:.|::||:|..|:.|.|
Mouse   310 TSSALSFALYLLAIHPDVQKKLQDEIDAAL-PNKAPATYDTLLQMEYLDMVVNETLRLYPIAGRL 373

  Fly   375 IRVATQHYQHTNPKYN---IEKGTGVIVPTLAIHHDPEFYPEPEKFIPERFDEDQVQQRPACTFL 436
            .||.     .|:.:.|   |.|||.|::||.|:|.||:::||||:|.||||.:..........:|
Mouse   374 ERVC-----KTDVEINGLFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSKKNQDSINPYMYL 433

  Fly   437 PFGDGPRNCIGLRFGRMQVIVGMALLIHNFKFEFHPTK-TVVPLEYRTDDFLLSSKGGIHLKV 498
            |||.|||||||:||..:.:.|.:..::.||..:  |.| |.:||:. :...||..:..:.|||
Mouse   434 PFGSGPRNCIGMRFALINMKVALVRVLQNFTVQ--PCKETEIPLKL-SKQGLLQPENPLLLKV 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a20	NP_611002.3	CYP6-like	67..495	CDD:410679	144/445 (32%)
Cyp3a13	NP_031845.1	CYP3A	67..492	CDD:410743	146/455 (32%)