Protein Alignment Cyp6a20 and CYP4F22

DIOPT Version :10

• Sequence 1: NP_611002.3
• Gene: Cyp6a20 / 36664
• FlyBaseID: FBgn0033980
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_775754.2
• Gene: CYP4F22 / 126410
• HGNCID: 26820
• Length: 531
• Species: Homo sapiens
• Alignment Length: 398
• Identity: 105/398 - (26%)
• Similarity: 184/398 - (46%)
• Gaps: 27/398 - (6%)

  Fly   115 LSANLVNIDGQKWKTLRQKLTPTFTSGKMKTMFPTILTVGDELIRVFGETASADSDSMEITNVVA 179
            |...|:...|.||...|:.|||.|....:|..........|.:...:...|...:.|:::...::
Human   140 LGDGLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204

  Fly   180 RFTADVIGSCAFGLDCH---SLSDPKAKFVQMGTTAITERRHGKSMDLLLFGAPELAAKLRMKAT 241
            ..|.|.:..|.|..:.:   .:||..:..:::  :|::.||..:....|.|.....|...|.:..
Human   205 LMTLDSLQKCVFSYNSNCQEKMSDYISAIIEL--SALSVRRQYRLHHYLDFIYYRSADGRRFRQA 267

  Fly   242 VQEVEDFYMNIIRD----------TVDYRVKNNVKRHDFVDMLIEMKLKFDNGDKENGLTFNEIA 296
            ...|..|...:|::          ....:.|.. |..||:|:|:   |..|...||  |:..:|.
Human   268 CDMVHHFTTEVIQERRRALRQQGAEAWLKAKQG-KTLDFIDVLL---LARDEDGKE--LSDEDIR 326

  Fly   297 AQAFIFFLAGFETSSTTMGFALYELACHQDIQDKLRTEINTVLK-QHNGKLDYDSMREMTYLEKV 360
            |:|..|...|.:|:|:.:.:.|:.||.:.:.|:|.|.||..|:| :...:|::|.:.::.:....
Human   327 AEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPFTTMC 391

  Fly   361 IDETMRKRPVVGHLIRVATQHYQHTNPKYNIEKGTGVIVPTLAIHHDPEFYPEPEKFIPERFDED 425
            |.|::|:.|.|..:.|..|:..:..:.:. |.||...:|.....||:|..:|:.:.:.|.|||.|
Human   392 IKESLRQYPPVTLVSRQCTEDIKLPDGRI-IPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPD 455

  Fly   426 QVQQRPACTFLPFGDGPRNCIGLRFGRMQVIVGMALLIHNFKFEFHPTKTVVPLEYRTDDFLLSS 490
            ..|||....::||..|||||||..|...::.|.:||.:..|:.....|:.|    .|..:.:|.:
Human   456 NPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRKV----RRKPELILRT 516

  Fly   491 KGGIHLKV 498
            :.|:.|||
Human   517 ENGLWLKV 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a20	NP_611002.3	CYP6-like	67..495	CDD:410679	102/393 (26%)
CYP4F22	NP_775754.2	CYP4F	82..523	CDD:410772	102/395 (26%)