DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a9 and CYP715A1

DIOPT Version :9

Sequence 1:	NP_523748.2	Gene:	Cyp6a9 / 36663	FlyBaseID:	FBgn0013771	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_200053.2	Gene:	CYP715A1 / 835316	AraportID:	AT5G52400	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	548	Identity:	134/548 - (24%)
Similarity:	223/548 - (40%)	Gaps:	101/548 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VYSVLLAIVVVLVGYLLLK-------WR-RALHYWQNLDIPCEEPHILMGSLTG----------V 49
            |:.:...:.||::..:.||       |. ||....:........|....|:|..          |
plant     9 VWYIFFKVFVVVICLMFLKLFLRCWIWPVRAQKKLRGNGFVGPAPSFPFGNLNDMKKLKMASVVV 73

  Fly    50 QTSRSFSAI--------------WMDYYNKFRGTGPFAGFYWFQ-RPGILVLDIS----LAKLIL 95
            ..|:|.:.|              |...|.|       ...||.. .|.:.|.|..    ::|.:|
plant    74 DNSKSSTIINHDIHSIALPHFARWQQEYGK-------VFVYWLGIEPFVYVADPEFLSVMSKGVL 131

  Fly    96 IKEFNK----FTDRGFYHNTEDDPLSGQ-LFLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVG 155
            .|.:.|    ..||        :|:.|. |.:::|..|...|..::..|....:|.|...:|:..
plant   132 GKSWGKPNVFKKDR--------EPMFGTGLVMVEGDDWTRHRHIITPAFAPLNLKVMTNMMVESV 188

  Fly   156 HEFIEVFG-QAMEKSPIVEVRDILARFTTDVIGTCAFGIECSS----LKDPEA-EFRVMGRRAIF 214
            ...::.:| |....:|..::...:.....::|...:||:...:    ||:..| :|      |:|
plant   189 SNMLDRWGIQINSGNPEFDMESEIIGTAGEIIAKTSFGVTGENGTQVLKNLRAVQF------ALF 247

  Fly   215 EQRHGPIGIAFINSFQNLARRLHMKITLEEAEHFFLRIVRETVAFREKNNIRRNDFMDQLIDLKN 279
            .... .:|:.|.|.       |..|.|: :|:.....|....::|..|..|...:..||..||..
plant   248 NSNR-YVGVPFSNI-------LSYKQTV-KAKGLGHEIDGLLLSFINKRKISLAEGDDQGHDLLG 303

  Fly   280 SPLTKSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGK 344
            ..|...:.|   |.|.:|:..:...||.||.||::..:.:....||.|.:.||.:|:|.:||||
plant   304 MLLKADQKG---NFTAKELVDECKTFFFAGHETTALALTWTFMLLAIHPEWQDTIREEIREVIG- 364

  Fly   345 YNGEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMH 409
             :.:|.|..:..:..:..|::|.||||...|...|:...|.||.|.   ||..|..:.|...|||
plant   365 -DSKIEYNKLAGLKKMSWVMNEVLRLYPPAPNAQRQARNDIEVNGR---VIPNGTNIWIDVVAMH 425

  Fly   410 RDEKLYANPNTFNPDNFSPERVKE------RDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLIN 468
            .|.:|:.:    :.:.|.|||...      ::.:.::|||.|.|.|||.....|:.:..|:|:::
plant   426 HDVELWGD----DVNEFKPERFDGNLHGGCKNKMGYMPFGFGGRMCIGRNLTTMEYKIVLSLVLS 486

  Fly   469 RFKFSVCEQTTIPIVYSKKTFLISSETG 496
            ||:.||.     |......|:::|...|
plant   487 RFEISVS-----PGYRHSPTYMLSLRPG 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	p450	35..499	CDD:278495	126/508 (25%)
CYP715A1	NP_200053.2	p450	16..519	CDD:299894	133/541 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900