DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a9 and CYP705A12

DIOPT Version :9

Sequence 1:	NP_523748.2	Gene:	Cyp6a9 / 36663	FlyBaseID:	FBgn0013771	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_199072.1	Gene:	CYP705A12 / 834265	AraportID:	AT5G42580	Length:	499	Species:	Arabidopsis thaliana

Alignment Length:	535	Identity:	110/535 - (20%)
Similarity:	224/535 - (41%)	Gaps:	105/535 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LAIVVVLVGYLLLKWRRALHYWQNLDIPCEEP---------HILMGSLTGVQTSRSFSAIWMDYY 63
            ::|.::|..:..|.:.......:..|:|...|         |:|..||    ..:||..:...|
plant    12 ISIFILLCLFSFLCYALFFKKPKGFDLPPSPPSLPIIGHLHHLLSSSL----PHKSFQKLSFKY- 71

  Fly    64 NKFRGTGPFAGFYWFQRPGILVLDISLA-KLILIKEFN---KFTDRGFYHNTEDDPL----SGQL 120
                  ||......|..|.:||...|:| ::....:.|   :|..      ...|.|    ||.:
plant    72 ------GPLLHLRIFNFPMVLVSSASMAYEVFRTNDVNVSYRFVP------VNKDSLVFGSSGFV 124

  Fly   121 FLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVG--------HEF-IEVFGQAMEKSPIVEVRD 176
            ....|..||.|:..:|       .|.:.|..:::.        ..| :::.|:|.:|.. ||:..
plant   125 TAPYGDYWKFMKKLIS-------TKLLRPHALELSKGNRAEELRRFCLDLQGKARKKES-VEIGK 181

  Fly   177 ILARFTTDVIGTCAFGIECSSLKDPEAEFRVMGRRAIFEQRHGPIGIAFINS----FQNLARRLH 237
            :..:.|.::|...:.|..||.            :..:.|:....:..:|..|    |.|:.|:..
plant   182 VALKLTNNIICRMSMGRSCSE------------KNGVAERARELVNKSFALSVKLFFSNMFRKDI 234

  Fly   238 MKITLEEAEHFFLRIVRETVAFREKN--NIRRNDFMDQLIDLKNSPLTKSESGESVNLTIEEMAA 300
            |.:: .|.:.|..||:.|    .|:|  ..:..|.:|.|::     ..::|..| ..:|.:::.:
plant   235 MGVS-REFDEFLERILVE----HEENLEGDQDRDMIDHLLE-----AYRNEEAE-YKITRKQIKS 288

  Fly   301 QAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGE--ITYESMKDMVYLDQV 363
            .....|..|.::|:.|:.:.:.|:..:..:.:::|.|...|:|   |:  |....:.::.||..|
plant   289 LIVEIFLGGTDSSAQTIQWTMAEILNNPGVLEKLRAEIDSVVG---GKRLIQESDLPNLPYLQAV 350

  Fly   364 ISETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNF-- 426
            :.|.|||:...|||.|...|..||   .::.:.:...:::...|::||...:.:|:.|.|:.|
plant   351 VKEGLRLHPSAPVLLRVFGESCEV---KEFYVPEKTTLVVNLYAVNRDPDSWEDPDMFKPERFLV 412

  Fly   427 -----SPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVCEQTTIPIVYSK 486
                 ..|:::|: :|:::.||.|.|.|..::...:...:.:..::..|.:.         :..:
plant   413 SSISGDEEKIREQ-AVKYVTFGGGRRTCPAVKLAHIFMETAIGAMVQCFDWR---------IKGE 467

  Fly   487 KTFLISSETGIFLKV 501
            |.::..:.:|:.||:
plant   468 KVYMEEAVSGLSLKM 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	p450	35..499	CDD:278495	104/504 (21%)
CYP705A12	NP_199072.1	CYP93	72..490	CDD:410748	97/464 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D467733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010