DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a9 and CYP735A1

DIOPT Version :9

Sequence 1:	NP_523748.2	Gene:	Cyp6a9 / 36663	FlyBaseID:	FBgn0013771	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_198661.1	Gene:	CYP735A1 / 833833	AraportID:	AT5G38450	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	526	Identity:	130/526 - (24%)
Similarity:	228/526 - (43%)	Gaps:	77/526 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SVLLAIVVVLVGYLLLKWRRALH-----YW----------QNLDIPCEEPHILMGSLTGVQTSRS 54
            ::|.:::|:.|..:|    |.|:     ||          :...:...:|..|.|::..:....|
plant     4 TILKSLLVIFVTTIL----RVLYDTISCYWLTPRRIKKIMEQQGVTGPKPRPLTGNILEISAMVS 64

  Fly    55 FSA--------------------IWMDYYNK----FRGTGPFAGFYWFQRPGILVLDISLAKLIL 95
            .||                    .|...|.|    :.||.          |.:.:.:..|.|.:|
plant    65 QSASKDCDSIHHDIVGRLLPHYVAWSKQYGKRFIVWNGTD----------PRLCLTETELIKELL 119

  Fly    96 IKEFNKFTDRGFYHNTEDDPLSGQ-LFLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFI 159
            :|. |..:.|.:..........|: |.:.:||.|...|...:..||..::|.....:|:...:.:
plant   120 MKH-NGVSGRSWLQQQGTKNFIGRGLLMANGQDWHHQRHLAAPAFTGERLKGYARHMVECTSKLV 183

  Fly   160 EVFGQAM-EKSPIVEVRDILARFTTDVIGTCAFGIECSSLKDPEAEFRVMGRRAIFEQRH--GPI 221
            |...:.: |.:..||:.:.:.:.|.|:|....||......|:......|:.||.....||  .|
plant   184 ERLRKEVGEGANEVEIGEEMHKLTADIISRTKFGSSFEKGKELFNHLTVLQRRCAQATRHLCFP- 247

  Fly   222 GIAFINSFQNLARRLHMKITLEEAEHFFLRIV--RETVAFREKNNIRRNDFMDQLIDLKNSPLTK 284
            |..|:.|..|    ..:|...:|.|...:.|:  |...|...:::...:|.:..|::..:.....
plant   248 GSRFLPSKYN----REIKSLKKEVERLLIEIIQSRRDCAEMGRSSTHGDDLLGLLLNEMDIDKNN 308

  Fly   285 SESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEI 349
            :.:..::.|.::|..    .||.||.||::..:.:....||.:...|::||:|.:||.|: ||..
plant   309 NNNNNNLQLIMDECK----TFFFAGHETTALLLTWTTMLLADNPTWQEKVREEVREVFGR-NGLP 368

  Fly   350 TYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKL 414
            :.:.:..:..|.:||:|:||||....:|.|...||.::   ....|.||:.:.||..|:|..|:|
plant   369 SVDQLSKLTSLSKVINESLRLYPPATLLPRMAFEDLKL---GDLTIPKGLSIWIPVLAIHHSEEL 430

  Fly   415 YA-NPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVCEQ- 477
            :. :.|.|||:.|.....  .....::||..|||||||.:|..|:|:..||.||::|.|::.:.
plant   431 WGKDANQFNPERFGGRPF--ASGRHFIPFAAGPRNCIGQQFALMEAKIILATLISKFNFTISKNY 493

  Fly   478 TTIPIV 483
            ...|||
plant   494 RHAPIV 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	p450	35..499	CDD:278495	122/481 (25%)
CYP735A1	NP_198661.1	PLN02290	1..518	CDD:215164	130/526 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910