DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a9 and CYP72A10

DIOPT Version :9

Sequence 1:	NP_523748.2	Gene:	Cyp6a9 / 36663	FlyBaseID:	FBgn0013771	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_188082.2	Gene:	CYP72A10 / 820692	AraportID:	AT3G14640	Length:	536	Species:	Arabidopsis thaliana

Alignment Length:	555	Identity:	137/555 - (24%)
Similarity:	219/555 - (39%)	Gaps:	129/555 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGVYSVLLAIVVVLVGYLLLKWRRALHYW----------------------------QNLDIPCE 37
            :.|..|.:::|||:|.:.:  ||.....|                            :|:::..|
plant    25 ISVACVTVSVVVVVVSWWV--WRTLQWVWFKPKMLESYLRRQGLAGTPYTPLIGDLKRNVNMLTE 87

  Fly    38 ---EPHILMGSLTGVQTSRSFSAIWMDYYNKFRGTGPFAGFYWFQRPGILVLDISLAKLILIKEF 99
               :|..|...:|.......|..:.......|...||        :|.|.::|..|.|.:    |
plant    88 ATSKPIKLTEDITPRVLPHPFQMLKTHGRTFFTWLGP--------KPTITIMDPELIKEV----F 140

  Fly   100 NKFTDRGFYHNTEDDPLSGQLFLL-----------DGQKWKSMRSKLSYTFTSGKMKYMFPTVVK 153
            ||..|..          ..|.|||           ||.||...|..::..|...|:|.|.|...:
plant   141 NKVYDYP----------KAQTFLLGRLIATGIINYDGDKWAKHRRIINPAFHIEKIKNMVPAFHQ 195

  Fly   154 -----VGHEFIEVFGQAMEKSPIVEVRDILARFTTDVIGTCAFGIECSSLKDPEAEFRVMGRRAI 213
                 || |:.::.......|..|:|...|...|.|||...|||   ||.|:        |:| |
plant   196 SCSDVVG-EWSKLVSDKGSSSCEVDVWPWLVSMTGDVISRTAFG---SSYKE--------GQR-I 247

  Fly   214 FEQRHGPIGI-------AFINSFQNLARRLH--MKITLEEAEHFFLRIVRETVAFREKNNIRRND 269
            ||.:...:.:       .:|..::.|..:.:  ||....|.:.....||.:.:..||......||
plant   248 FELQAELVHLILQAFWKVYIPGYRYLPTKSNRRMKAAAREIQVILKGIVNKRLRAREAGKAAPND 312

  Fly   270 FMDQLIDLKNSPLTKSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRV 334
              |.|..|..|.|.:::..   .::.|::..:..:|:.||.||:|..:.:|:..|:.|||.|.|.
plant   313 --DLLGILLESNLGQAKGN---GMSTEDVMEECKLFYFAGQETTSVLLVWAMVLLSHHQDWQARA 372

  Fly   335 RKECQEVIGKYNGEITYESMKDMVYLDQVISETLRLYTVLPVLNREC-----LEDYEVPGHPKYV 394
            |:|.::|.|  :.|...|.:..:..:..::.|.||||..:..|.|..     |.|..:|.
plant   373 REEVKQVFG--DKEPDTECLSQLKVMTMILYEVLRLYPPVTHLTRAIDKEMKLGDLTLPA----- 430

  Fly   395 IKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKE------RDSVEWLPFGDGPRNCIGMR 453
               |:.:.:|...:.||..|:..    :...|.|||.|:      :..|.:.||..|||.|||..
plant   431 ---GVHISLPIMLVQRDPMLWGT----DAAEFKPERFKDGLSKATKSQVSFFPFAWGPRICIGQN 488

  Fly   454 FGQMQARSGLALLINRFKFSV------CEQTTIPI 482
            |..::|:..:||::..|.|.:      ..||.:.|
plant   489 FAMLEAKMAMALILQTFTFELSPSYVHAPQTVVTI 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	p450	35..499	CDD:278495	127/493 (26%)
CYP72A10	NP_188082.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810