Protein Alignment Cyp6a9 and Cyp4x1

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001003947.1
• Gene: Cyp4x1 / 81906
• MGIID: 1932403
• Length: 507
• Species: Mus musculus
• Alignment Length: 542
• Identity: 132/542 - (24%)
• Similarity: 232/542 - (42%)
• Gaps: 104/542 - (19%)

  Fly     8 LAIVVVLVGYLLLKWRRALHYWQNLD-IPCEEPHILMGSLTGVQTSR-------------SFSAI 58
            ||:|::....|.|:.:|.|   ::|. .|....|.|:|....:|...             :|..
Mouse    22 LALVLMQAMKLYLRRQRLL---RDLSPFPGPPAHWLLGHQKFLQEDNMETLDEIVKKHPCAFPC- 82

  Fly    59 WMDYYNKFRGTGPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSGQLFLL 123
            |:         |||..|::       :.|...||:.|.:...|..   :.|......:...|..|
Mouse    83 WV---------GPFQAFFY-------IYDPDYAKIFLSRTDPKMQ---YLHQLLTPCIGRGLLNL 128

  Fly   124 DGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEK-----SPIVEVRDILARFTT 183
            ||.:|...|..|:..|....:|   |.|..:.|. ::|.....||     ...:||.:.:...|.
Mouse   129 DGPRWFQHRCLLTPAFHQDILK---PCVDTMAHS-VKVMLDKWEKMWTTQETTIEVFEHINLMTL 189

  Fly   184 DVIGTCAFGIECSSLKDPEAEFRVMGRRAIFE-------------QRH------GPIGIAFINSF 229
            |:|..||||.|.:...:...|..|   :|.||             ..|      .|.|    :.|
Mouse   190 DIIMKCAFGQETNCQINGTYESYV---KATFELGEIISSRLYNFWHHHDIIFKLSPKG----HCF 247

  Fly   230 QNLARRLHMKITLEEAEHFFLRIVRETVAFREKNNIRRND------FMDQLIDLKNSPLTKSESG 288
            |.|.:.:|         .:..:|:::..... ||.::::|      |:|.::        .:::.
Mouse   248 QELGKVIH---------QYTEKIIQDRKKIL-KNQVKQDDTQTSQIFLDIVL--------SAQAE 294

  Fly   289 ESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEITYES 353
            :....:..::.|:...|..||.:.|:.::.:.||.||.:.:.|||.|.|.:.::|. ...||:|.
Mouse   295 DERAFSDADLRAEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRTEIRSILGD-GSSITWEQ 358

  Fly   354 MKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVP-GHPKYVIKKGMPVLIPCGAMHRDEKLYAN 417
            :.:|.|....|.|||||...:|.::||..:...:| ||.   :..||.|::....:|.:..::.:
Mouse   359 LDEMSYTTMCIKETLRLIPPVPSISRELSKPLTLPDGHS---LPAGMTVVLSIWGLHHNPAVWND 420

  Fly   418 PNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVCEQTTIPI 482
            |..|:|..|:.|...:|....:|||..|||||||.:|..::.:..:||::  ..|.|....|.|.
Mouse   421 PKVFDPLRFTKENSDQRHPCAFLPFSSGPRNCIGQQFAMLELKVAIALIL--LHFQVAPDLTRPP 483

  Fly   483 VYSKKTFLISSETGIFLKVERV 504
            .:|..| ::..:.||:|.::::
Mouse   484 AFSSHT-VLRPKHGIYLHLKKL 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	115/460 (25%)
Cyp4x1	NP_001003947.1	CYP4B-like	66..500	CDD:410771	118/489 (24%)