DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6a9 and BAS1

DIOPT Version :9

Sequence 1:	NP_523748.2	Gene:	Cyp6a9 / 36663	FlyBaseID:	FBgn0013771	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_180239.1	Gene:	BAS1 / 817212	AraportID:	AT2G26710	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	523	Identity:	137/523 - (26%)
Similarity:	230/523 - (43%)	Gaps:	75/523 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VYSVLLAIVVVLVGYLLLKW--RRALHYWQNLDIPCEEPHILMGS---LTGVQTSRSFSAI---- 58
            |.||:|::|:| .|..||.|  |:...::....|.....|..:|:   |.|:....|...:
plant    15 VLSVILSLVIV-KGMSLLWWRPRKIEEHFSKQGIRGPPYHFFIGNVKELVGMMLKASSHPMPFSH 78

  Fly    59 -----WMDYYNKFRGTGPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSG 118
                 .:.:|:.:|.........||..    ...:::|...||:|.  |:...||...|..||..
plant    79 NILPRVLSFYHHWRKIYGATFLVWFGP----TFRLTVADPDLIREI--FSKSEFYEKNEAHPLVK 137

  Fly   119 Q-----LFLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDIL 178
            |     |..|.|:||...|..:|.||....:|.:.|.|:|...:.::.:...:.::..||| |:.
plant   138 QLEGDGLLSLKGEKWAHHRKIISPTFHMENLKLLVPVVLKSVTDMVDKWSDKLSENGEVEV-DVY 201

  Fly   179 ARF---TTDVIGTCAFGIECSSLKDPEAEFRVMGRRAI-----FEQRHGPIGIAFINSFQNLARR 235
            ..|   |.|||...|||   ||.:|..|.||:..::.:     |::       .||..::....|
plant   202 EWFQILTEDVISRTAFG---SSYEDGRAVFRLQAQQMLLCAEAFQK-------VFIPGYRFFPTR 256

  Fly   236 LHMKITL--EEAEHFFLRIVRETVAFREKNNIRRNDFMDQLIDLKNSPLTKSESG---ESVNLTI 295
            .::|...  :|.....|:::..          ||.:.:|...:....|..|...|   ::.|:|:
plant   257 GNLKSWKLDKEIRKSLLKLIER----------RRQNAIDGEGEECKEPAAKDLLGLMIQAKNVTV 311

  Fly   296 EEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEITYESMKDMVYL 360
            :::..:...||.||.:|:|..:.:....|:.|.:.|.:.|.|...|.|..:.. |.:.:..:..|
plant   312 QDIVEECKSFFFAGKQTTSNLLTWTTILLSMHPEWQAKARDEVLRVCGSRDVP-TKDHVVKLKTL 375

  Fly   361 DQVISETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANP-NTFNPD 424
            ..:::|:||||..:....|....|.::.|   |.|..|..:|||..|:|.|:.::.|. |.|||.
plant   376 SMILNESLRLYPPIVATIRRAKSDVKLGG---YKIPCGTELLIPIIAVHHDQAIWGNDVNEFNPA 437

  Fly   425 NFS---PERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVC-----EQTTIP 481
            .|:   |...|.  .|.::|||.|.|.|||.....:||:..||::|.||.|.:.     ..|.:.
plant   438 RFADGVPRAAKH--PVGFIPFGLGVRTCIGQNLAILQAKLTLAVMIQRFTFHLAPTYQHAPTVLM 500

  Fly   482 IVY 484
            ::|
plant   501 LLY 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	p450	35..499	CDD:278495	125/489 (26%)
BAS1	NP_180239.1	CYP734	85..509	CDD:410732	120/452 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810