Protein Alignment Cyp6a9 and Cyp4a31

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_964002.2
• Gene: Cyp4a31 / 666168
• MGIID: 3028580
• Length: 509
• Species: Mus musculus
• Alignment Length: 542
• Identity: 129/542 - (23%)
• Similarity: 225/542 - (41%)
• Gaps: 97/542 - (17%)

  Fly     3 VYSVLLAIVVVLVGYLLLKWRRALHYWQNLDIPCEEPHILMGSLTGVQTSRSFSAIWMDYYNKFR 67
            |:.:||.:|..:..||..||                      .|..:|...|....|...:.:|:
Mouse    24 VFCLLLLLVKAVQVYLHRKW----------------------LLKALQQFPSPPFHWFFGHEQFK 66

  Fly    68 G--------------TGPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSG 118
            |              ...|..::|..:..:.|.|....|:||.:...|  ..|.|....  |..|
Mouse    67 GDQELQEIVSCIENFPSAFPRWFWGSKAYLTVYDPDYMKVILGRSDPK--ANGAYRLLA--PWIG 127

  Fly   119 Q-LFLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEK----SPIVEVRDIL 178
            . |.||:||.|...|..|:..|....:|    |.||...:.|.:.....|:    ...:|:...:
Mouse   128 YGLLLLNGQSWFQHRKMLTPAFHYDILK----TYVKNMADSIRLMLDKWERLAGQDSSIEIFQHI 188

  Fly   179 ARFTTDVIGTCAFGIECSSLKDPEAEFRVMGRRAIFEQRHGPIGIAFINSFQNLARRLHMKITLE 243
            :..|.|.:..|||        ..:...:|.|....:.|..|.:.....:..:|:   .|...|:.
Mouse   189 SLMTLDTVMKCAF--------SHKGSVQVDGNYKTYLQAIGDLNNLVHSRVRNM---FHQNDTIY 242

  Fly   244 EA---------------EHF--FLRIVRETVAFR-EKNNI---RRNDFMDQLIDLKNSPLTKSES 287
            :.               :|.  .:::.::.:... |..||   ||.||:|.|:      ..:.|:
Mouse   243 KLSSNGRLSNQACQLAHDHTDGVIKMRKDQLQDEGELENIKKKRRLDFLDILL------FARMEN 301

  Fly   288 GESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEITYE 352
            .:|  ::.:::.|:...|...|.:|:::.:.:..|.||.|.:.|.|.|:|.|.::|. ...||::
Mouse   302 EDS--MSDKDLRAEVDTFMIEGHDTTASGVSWIFYALATHPEHQQRCREEVQSLLGD-GSSITWD 363

  Fly   353 SMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYAN 417
            .:..:.|....|.|.||||..:|.:.||.......|....  :.||:.|.:....:|.:.|::.|
Mouse   364 HLDQIPYTTMCIKEALRLYPPVPSIGRELSTSVTFPDGCS--LPKGVQVTLSIYGLHHNPKVWPN 426

  Fly   418 PNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVCEQTTIPI 482
            |..|:|..|:|:  ..|.|..:|||..|.|||||.:|...:.:..:||.:.||:. :.:.|.:|:
Mouse   427 PEVFDPSRFAPD--SPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFEL-LPDPTRVPM 488

  Fly   483 VYSKKTFLISSETGIFLKVERV 504
              |...|::.|:.||:|.:::|
Mouse   489 --SLARFVLKSKNGIYLHLKKV 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	113/469 (24%)
Cyp4a31	NP_964002.2	CYP4B-like	71..504	CDD:410771	113/467 (24%)