Protein Alignment Cyp6a9 and CYP4F11

DIOPT Version :9

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001122404.1
• Gene: CYP4F11 / 57834
• HGNCID: 13265
• Length: 524
• Species: Homo sapiens
• Alignment Length: 550
• Identity: 141/550 - (25%)
• Similarity: 248/550 - (45%)
• Gaps: 109/550 - (19%)

  Fly    10 IVVVLVG--YLL---LKWRRALH-----------------YW--QNLDIPCEEPHILMGSLTGVQ 50
            ::::|||  :||   |.|....:                 :|  |.|..|.||.   |.:||.:.
Human    20 LLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWFWGHQGLVTPTEEG---MKTLTQLV 81

  Fly    51 TS--RSFSAIWMDYYNKFRGTGPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHNTED 113
            |:  :.|. :|:         ||.........|.|:....|.:..:..|:...:   ||.
Human    82 TTYPQGFK-LWL---------GPTFPLLILCHPDIIRPITSASAAVAPKDMIFY---GFL----- 128

  Fly   114 DPLSGQ-LFLLDGQKWKSMRSKLSYTFTSGKMK-YM--FPTVVKVGHEFIEVFGQAMEKSPIVEV 174
            .|..|. |.|..|.||...|..|:..|....:| ||  |...|.:.|:..:..  |.|.|..:::
Human   129 KPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRL--ASEGSARLDM 191

  Fly   175 RDILARFTTDVIGTCAFGIECSSLKDPEAEF--RVMGRRAIFEQRH-------------GPIGIA 224
            .:.::..|.|.:..|.|..| |:.::..:|:  .::...|..|:|:             .|.|
Human   192 FEHISLMTLDSLQKCVFSFE-SNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDG-- 253

  Fly   225 FINSFQNLARRLHMKITLEEAEHFFLRIVRE---TVAFREKNNIRRN-------DFMDQLIDLKN 279
                 |...|..|:.....:|      :::|   |:..:..::..:|       ||:|.|:
Human   254 -----QRFRRACHLVHDFTDA------VIQERRCTLPTQGIDDFLKNKAKSKTLDFIDVLL---- 303

  Fly   280 SPLTKSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVI-G 343
              |:|.|.|:  .|:.|::.|:|..|...|.:|:::.:.:.||.||:|.:.|::.|:|.||:: .
Human   304 --LSKDEDGK--ELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKD 364

  Fly   344 KYNGEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVP-GHPKYVIKKGMPVLIPCGA 407
            :...||.::.:..:.:|...|.|:|||:..:||::|.|.:|:.:| |.   ||.||:..||....
Human   365 REPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGR---VIPKGIVCLINIIG 426

  Fly   408 MHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKF 472
            :|.:..::.:|..::|..|..|.:|||..:.::||..|||||||..|...:.:..|||.:..|:
Human   427 IHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFR- 490

  Fly   473 SVCEQTTIPIVYSKKTFLISSETGIFLKVE 502
             :....|.|  ..|...::.:|.|::|:||
Human   491 -ILPTHTEP--RRKPELILRAEGGLWLRVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	p450	35..499	CDD:278495	128/496 (26%)
CYP4F11	NP_001122404.1	p450	52..506	CDD:365848	129/505 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810