Protein Alignment Cyp6a9 and cyp4v2a

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001071070.1
• Gene: cyp4v2a / 558851
• ZFINID: ZDB-GENE-061103-601
• Length: 513
• Species: Danio rerio
• Alignment Length: 548
• Identity: 125/548 - (22%)
• Similarity: 227/548 - (41%)
• Gaps: 90/548 - (16%)

  Fly     1 MGVYS---VLLAIVVVLVGYL---LLKWRRALHYWQNL-DIP-CEEPHILMGSLTGVQTSRSFSA 57
            :|||:   |..::.|:...|:   |||  ..||.|:.| .|| .......:|:....:::..|..
Zfish     5 VGVYTYGFVAASVCVICFAYITYQLLK--SYLHKWKELKPIPGIGNTFPFIGNALQFKSNGDFFL 67

  Fly    58 IWMDYYNKFRGT-------GPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDP 115
            ..:.|..:|:.:       ||.        |.:::......:.:|....:  .|:.:.:......
Zfish    68 QLVGYTTEFQNSPLLKIWIGPI--------PFLILFHAETVETVLNNPVH--IDKAYAYQFLHPW 122

  Fly   116 LSGQLFLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILAR 180
            |...|....|.||:..|..|:.||...    :....::|.:|..||..:.:||.......:..:.
Zfish   123 LGTGLLTSTGDKWRRRRKMLTPTFHFS----ILTEFLEVMNEQAEVLIEKLEKQAGKGPFNCFSH 183

  Fly   181 FTTDVIGTCAFGIECSSLKDPEAEFRVMGRRAIFEQRHGPIGIAFINSFQN-LARRLHM------ 238
            .|     .||..|.|.:         .||:|...:..:....:..:....: :.||..|
Zfish   184 IT-----LCALDIICET---------AMGKRIYAQSNYDSEYVRTVYRMSDIITRRQRMPWYWPD 234

  Fly   239 ---KITLEEAEH---------FFLRIVRETVAF---------REKNNIRRNDFMDQLIDLKNSPL 282
               ....|..||         |...::.|...:         .::...:|..|:|.|:.
Zfish   235 FVYNYVGEGREHNRSLKILHSFTESVINERAEYLSYVESDSESDQGMRKRRAFLDMLLK------ 293

  Fly   283 TKSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNG 347
            ||.|.|:.  ||.:::..:...|...|.:|::..|.:|::.|..|.::|.:.::|..||.|:...
Zfish   294 TKDEDGKM--LTHKDIQEEVDTFMFEGHDTTAAAMNWAIHLLGSHPEVQRKAQQELFEVFGESER 356

  Fly   348 EITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDE 412
            .:..|.:|.:.||:.||.|:|||:..:|...|...:|.::.|   :.:.||..:::...|:|||.
Zfish   357 PVNTEDLKKLRYLECVIKESLRLFPSVPFFARTICDDTQING---FKVPKGTNIVVITYALHRDP 418

  Fly   413 KLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVCE- 476
            :.:.:|..|.|:.|.||....|....::||..|.|||||.||..|:.:..||.::..|....|:
Zfish   419 RFFPDPEEFRPERFLPENCVGRHPYAYIPFSAGLRNCIGQRFAIMEEKVILAYILRYFNIVACQK 483

  Fly   477 -QTTIPIVYSKKTFLISSETGIFLKVER 503
             :...|:    ...::..|.||::.:||
Zfish   484 REELRPL----GELVLRPEQGIWITLER 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	103/466 (22%)
cyp4v2a	NP_001071070.1	cytochrome_P450	68..503	CDD:477761	106/477 (22%)