Protein Alignment Cyp6a9 and cyp26c1

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001025122.2
• Gene: cyp26c1 / 554036
• ZFINID: ZDB-GENE-050714-2
• Length: 554
• Species: Danio rerio
• Alignment Length: 583
• Identity: 116/583 - (19%)
• Similarity: 205/583 - (35%)
• Gaps: 175/583 - (30%)

  Fly     5 SVLLAIVVVLVGYLLLKWRRALHYWQ-NLDIPCEEPHILMGSLTGVQTSRSFSAIWMDYYNKFRG 68
            :||..::::.|..||.::|     |. ..|..|:.| :..||:.......:|.  |:     |:|
Zfish    18 AVLPTVLLLAVSRLLWEFR-----WSITRDRTCKLP-LPQGSMGWPLVGETFH--WL-----FQG 69

  Fly    69 T----------GPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSGQLFL- 122
            :          |.....:...:|.|.|......:.||:.|......:.        |.|.::.|
Zfish    70 SSFHISRREKHGKVFKTHLLGKPLIRVTGAENIRKILLGEHTVVCTQW--------PQSTRIILG 126

  Fly   123 ------LDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILARF 181
                  ..|...|..|..|:..|:.|.::.....:..|                   |:..:|::
Zfish   127 PNTLVNSVGDLHKRKRKVLAKVFSRGALEAYLTRLQDV-------------------VKSEIAKW 172

  Fly   182 TTDVIGTCAFGIECSSLKDPEAEFRVMGRRAI---FEQRHGPIGIAFIN-SFQNLARRLHMKITL 242
            .|:. |:........||     .||:..|..:   .|::.    |.::: :|:.|...|
Zfish   173 CTET-GSVEVYTAAKSL-----TFRIAVRVLLGLHLEEQQ----ITYLSKTFEQLMNNL------ 221

  Fly   243 EEAEHFFLRIVRETVAFREKNNIRRNDF----MDQLIDLKNSPLTKSESGE-------------- 289
                 |.|.|  :|.....:..||..:.    |:::|:.|   |.|.::.:
Zfish   222 -----FSLPI--DTPVSGLRKGIRAREILHSAMEKIIEEK---LKKQQASDYCDAFDYMLSSARE 276

  Fly   290 -SVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQ-------------- 339
             ...||::|:...|.....|...|:::.....:.:|.:|.|:.:|.|.|.:
Zfish   277 NDYELTMQELKETAVELIFAAHSTTASASTSLIMQLLRHPDVSERARAELESEGLITDGHGHCRS 341

  Fly   340 -------------------------------EVIGKYNGE--------ITYESMKDMVYLDQVIS 365
                                           |...|..|.        ::.|.:..:.|||.|:.
Zfish   342 RCNGNAISEEGEAAEKSTSDRRSAINKATYFEAGDKEEGRRSRTHVPYLSLEKLSQLSYLDCVVK 406

  Fly   366 ETLRLYTVLPVLN---RECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFS 427
            |.||.   ||.::   |..|:.:|:.|   |.|.||..|:......|...:.|.||..|:||.|.
Zfish   407 EVLRF---LPPVSGGYRTVLQTFELNG---YQIPKGWSVMYSIRDTHETAEAYQNPELFDPDRFC 465

  Fly   428 PERVKER-DSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVCEQT-----TIPIVY 484
            ..|.:.: :...::|||.|.|.|||.....:..::....|:.....::..||     |:|||:
Zfish   466 VGREESKSERFSYVPFGGGVRRCIGRELALIVLKTLAVELLATADCTLATQTYPRMQTVPIVH 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	101/519 (19%)
cyp26c1	NP_001025122.2	cytochrome_P450	59..537	CDD:477761	104/536 (19%)