Protein Alignment Cyp6a9 and cyp3a65

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001032515.2
• Gene: cyp3a65 / 553969
• ZFINID: ZDB-GENE-050604-1
• Length: 517
• Species: Danio rerio
• Alignment Length: 514
• Identity: 145/514 - (28%)
• Similarity: 263/514 - (51%)
• Gaps: 36/514 - (7%)

  Fly     4 YSVLLAIVVVLVGYLLLKWRRALHYWQNLDIPCEEPHILMGSLTGVQTSRSFSAIWMDYYNKFRG 68
            :::|..:|.:||.|  ..|..  .|::.|.||..:.....|::  ::....|....||.:.|:
Zfish     8 WTLLAFLVALLVIY--GSWPH--RYFKKLGIPGPKTIPFFGTM--LRYKDGFHVFDMDCFEKY-- 64

  Fly    69 TGPFAGFYWFQRPGILVLDISLAKLILIKE-FNKFTDRGFYHNTEDDPLSGQLF----LLDGQKW 128
             |...|.|..::|.:.::|.::.|.:|||| ::.||:|..:.      |:|.|:    :.:...|
Zfish    65 -GRIWGIYDGRQPVLCIMDQTIIKTVLIKECYSLFTNRRNFR------LNGALYDAVSIAEDDDW 122

  Fly   129 KSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILARFTTDVIGTCAFGI 193
            :.:||.||.:||||::|.||..:.|..|..::..|:..::....::::....::.||:.:.||.:
Zfish   123 RRIRSVLSPSFTSGRLKEMFGIMKKHSHILVDSMGKTAKRGESADIKEFFGAYSMDVVTSTAFSV 187

  Fly   194 ECSSLKDPEAEFRVMGRRAIFEQRHGPIG--IAFINSFQNLARRLHMKITLEEAEHFF------L 250
            :..||.:|:..|....::.:......|:.  |||......:..::...:.......||      :
Zfish   188 DIDSLNNPKDPFVTNIKKMLKFDLLNPLFLLIAFFPFMAPVLEKMDFALFPTSVTDFFYAALQKI 252

  Fly   251 RIVRETVAFREKNNIRRNDFMDQLIDLKNSPLTKSESGESV--NLTIEEMAAQAFVFFGAGFETS 313
            :..|:|....:.|..:|.||:..::|.:.....||: ||..  .|:..|:.:|:.:|..||:|||
Zfish   253 KSDRDTKTVAKDNTKKRVDFLQLMVDSQTGVKHKSD-GEHTEKGLSDHEILSQSMIFIFAGYETS 316

  Fly   314 STTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEITYESMKDMVYLDQVISETLRLYTVLPVLN 378
            |:|:.|..|.||.:.:...::::|..|.... ...:.||::..|.|||..:||:||||.|...|.
Zfish   317 SSTLSFLFYNLATNPETMKKLQEEIDETFPN-QAPVDYETLMSMDYLDAALSESLRLYPVAARLE 380

  Fly   379 RECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFG 443
            |.|.:..|:.|   .:|.|.:.|::|..|:|||...::.|.:|.|:.|:....:..|...::|||
Zfish   381 RVCKKTVEING---LLIPKDLVVMVPTYALHRDPDYWSEPESFKPERFTKGNKESIDPYMYMPFG 442

  Fly   444 DGPRNCIGMRFGQMQARSGLALLINRFKFSVCEQTTIPIVYSKKTFLISSETGIFLKVE 502
            .||||||||||.|:..:..:..::.||..|||::|.:|:...... |:|.:..|.||::
Zfish   443 LGPRNCIGMRFAQVTMKLAIVEILQRFDVSVCDETQVPLELGFNG-LLSPKDPIKLKLQ 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	127/444 (29%)
cyp3a65	NP_001032515.2	cytochrome_P450	63..498	CDD:477761	129/449 (29%)