Protein Alignment Cyp6a9 and CYP4F3

DIOPT Version :9

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_000887.2
• Gene: CYP4F3 / 4051
• HGNCID: 2646
• Length: 520
• Species: Homo sapiens
• Alignment Length: 431
• Identity: 118/431 - (27%)
• Similarity: 207/431 - (48%)
• Gaps: 66/431 - (15%)

  Fly   104 DRGFYHNTEDDPLSGQ-LFLLDGQKWKSMRSKLSYTFTSGKMK-YMFPTVVKVGHEFIEVFGQ-- 164
            |:.||...:  |..|. |.|..|:||...|..|:..|....:| ||     |:.:|.:.:...
Human   121 DKVFYSFLK--PWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYM-----KIFNESVNIMHAKW 178

  Fly   165 ---AMEKSPIVEVRDILARFTTDVIGTCAFGIECSSLKDPEAEF--RVMGRRAIFEQRHGPIGIA 224
               |.|.|..:::.:.::..|.|.:..|.|..: |..::..:|:  .::...|:..:||..| :.
Human   179 QLLASEGSARLDMFEHISLMTLDSLQKCVFSFD-SHCQEKPSEYIAAILELSALVTKRHQQI-LL 241

  Fly   225 FIN----------SFQNLARRLH--MKITLEEAEHFFLRIVRETVA-------FREKNNIRRNDF 270
            :|:          .|:...|.:|  ....::|.        |.|:.       .:.|...:..||
Human   242 YIDFLYYLTPDGQRFRRACRLVHDFTDAVIQER--------RRTLPSQGVDDFLQAKAKSKTLDF 298

  Fly   271 MDQLIDLKNSPLTKSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVR 335
            :|.|:      |:|.|.|:  .|:.|::.|:|..|...|.:|:::.:.:.||.||:|.:.|:|.|
Human   299 IDVLL------LSKDEDGK--KLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCR 355

  Fly   336 KECQEVI-GKYNGEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVP-GHPKYVIKKG 398
            :|.||:: .:...||.::.:..:.:|...|.|:|||:..:|.::|.|.:|..:| |.   ||.||
Human   356 QEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGR---VIPKG 417

  Fly   399 MPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRF--GQMQARS 461
            :..||.....|.:..::.:|..::|..|.|:.:|||..:.::||..|||||||..|  .:|:...
Human   418 IICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVL 482

  Fly   462 GLALLINRFKFSVCEQTTIPIVYSKKTFLISSETGIFLKVE 502
            ||.||    :|.|....|.|  ..|...::.:|.|::|:||
Human   483 GLTLL----RFRVLPDHTEP--RRKPELVLRAEGGLWLRVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	p450	35..499	CDD:278495	115/426 (27%)
CYP4F3	NP_000887.2	p450	52..515	CDD:365848	115/427 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810