DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a9 and Cyp6a21

DIOPT Version :9

Sequence 1:	NP_523748.2	Gene:	Cyp6a9 / 36663	FlyBaseID:	FBgn0013771	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_611003.2	Gene:	Cyp6a21 / 36665	FlyBaseID:	FBgn0033981	Length:	504	Species:	Drosophila melanogaster

Alignment Length:	504	Identity:	411/504 - (81%)
Similarity:	458/504 - (90%)	Gaps:	0/504 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGVYSVLLAIVVVLVGYLLLKWRRALHYWQNLDIPCEEPHILMGSLTGVQTSRSFSAIWMDYYNK 65
            |.|.:|||..::.||||||:|||..:.:||:|.||||||||||||:.||:|:|||:.||..||||
  Fly     1 MSVGTVLLTALLALVGYLLMKWRSTMRHWQDLGIPCEEPHILMGSMKGVRTARSFNEIWTSYYNK 65

  Fly    66 FRGTGPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSGQLFLLDGQKWKS 130
            |||:|||||||||:||.:.||:.||||.||||||||||||||:||.|||||||||||||||||::
  Fly    66 FRGSGPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLSGQLFLLDGQKWRT 130

  Fly   131 MRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILARFTTDVIGTCAFGIEC 195
            ||:|||.|||||||||||||||||.:||.:||||.:.|||:||||::||||||||||||||||||
  Fly   131 MRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVRELLARFTTDVIGTCAFGIEC 195

  Fly   196 SSLKDPEAEFRVMGRRAIFEQRHGPIGIAFINSFQNLARRLHMKITLEEAEHFFLRIVRETVAFR 260
            ||||||:||||.||||::.|||.||:||.|:|||.|||||||||:|.|..|.||:||||||||||
  Fly   196 SSLKDPDAEFREMGRRSLTEQRLGPVGIGFVNSFPNLARRLHMKMTAEPIERFFMRIVRETVAFR 260

  Fly   261 EKNNIRRNDFMDQLIDLKNSPLTKSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELA 325
            |:|||||||||||||||||.||..|:|||||||||||:||||||||.||||||||||||||||||
  Fly   261 EQNNIRRNDFMDQLIDLKNKPLMVSQSGESVNLTIEEIAAQAFVFFAAGFETSSTTMGFALYELA 325

  Fly   326 QHQDIQDRVRKECQEVIGKYNGEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGH 390
            |:||||:||||||||||.|.|||:.||||||:||||||:||||||||||||||||||||||||||
  Fly   326 QNQDIQNRVRKECQEVIEKCNGELNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPGH 390

  Fly   391 PKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFG 455
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   391 PKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFG 455

  Fly   456 QMQARSGLALLINRFKFSVCEQTTIPIVYSKKTFLISSETGIFLKVERV 504
            |||||.||||||..|||||||:||||:.|:|:.|||:|.:||:||.|||
  Fly   456 QMQARIGLALLIKDFKFSVCEKTTIPMTYNKEMFLIASNSGIYLKAERV 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	p450	35..499	CDD:278495	388/463 (84%)
Cyp6a21	NP_611003.2	p450	35..499	CDD:278495	388/463 (84%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471787
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	1	1.000	-	-		H130979
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	1	0.950	-	0	Normalized mean entropy	S7447
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	13	12.750