Protein Alignment Cyp6a9 and cyp26b1

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_997831.1
• Gene: cyp26b1 / 324188
• ZFINID: ZDB-GENE-030131-2908
• Length: 511
• Species: Danio rerio
• Alignment Length: 530
• Identity: 114/530 - (21%)
• Similarity: 202/530 - (38%)
• Gaps: 109/530 - (20%)

  Fly     5 SVLLAIVVVLVGYLLL------KWRRALHYWQNLDIPCEEPHILMGSLTGVQTSRSFSAIWMDYY 63
            |.|..:...||...||      .|:  |.:....|..|:.| :..||:       .|..|....:
Zfish    10 SALATLAACLVSMALLLAVSQQLWQ--LRWTATRDKSCKLP-MPKGSM-------GFPIIGETCH 64

  Fly    64 NKFRGTGPFAG----------FYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHN--TEDDPL 116
            ..|:|.|..|.          .:...||.|.|......:.:|:.|          |:  |.|.|.
Zfish    65 WFFQGAGFHASRRQKYGNVFKTHLLGRPLIRVTGAENVRKVLMGE----------HSLVTVDWPQ 119

  Fly   117 SGQLFL-------LDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEV 174
            |....|       ..|...:..|...:..|:...::...|.:.:|..|.:.|:  :....||...
Zfish   120 STSTLLGPNSLANSIGDIHRKRRKIFAKVFSHEALESYLPKIQQVIQETLRVW--SSNPDPINVY 182

  Fly   175 RDILARFTTDVIGTCAFGIECSSLKDPEAEFRVMGR------RAIFEQRHGPIGIAFINSFQNLA 233
            |: ..|.:.::......|     .:.||.|...:..      ..:|..   ||.:.|....:.:.
Zfish   183 RE-SQRLSFNMAVRVLLG-----FRIPEEEMHCLFSTFQEFVENVFSL---PIDLPFSGYRKGIR 238

  Fly   234 RRLHMKITLEEAEHFFLRIVRETVAFREKN-NIRRNDFMDQLIDLKNSPLTKSESGESVNLTIEE 297
            .|..::.::|:             |.|||. :.:..|:.|.|     ..|.:|....:..||::|
Zfish   239 ARDSLQKSIEK-------------AIREKPLHTQGKDYTDAL-----DVLLESAKENNTELTMQE 285

  Fly   298 MAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKE------------CQEVIGKYNGEIT 350
            :.........|.|.|:::.....:.:|.:|..:.:::|:|            ||       ||:.
Zfish   286 LKESTIELIFAAFATTASASTSLVMQLLRHPAVLEKLREELRSCGLLHDGCLCQ-------GELR 343

  Fly   351 YESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLY 415
            .:|:..:.|||.||.|.|||:..:....|...:.:|:.|   ..:.||..|:......|....::
Zfish   344 LDSIISLKYLDCVIKEVLRLFAPVSGGYRIATQTFELDG---VQVPKGWSVMYSIRDTHDTSAVF 405

  Fly   416 ANPNTFNPDNFSPERVKERDS-VEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVCEQT- 478
            .:...|:||.|||||.::|:. ..:||||.|.|:|:|.:...:..:.....|....:|.:..:|
Zfish   406 KDVEAFDPDRFSPERSEDREGRFHYLPFGGGVRSCLGKQLATLFLKLLAVELAGGSRFELSTRTF 470

  Fly   479 ----TIPIVY 484
                ::|:|:
Zfish   471 PRMISVPVVH 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	98/461 (21%)
cyp26b1	NP_997831.1	cytochrome_P450	60..489	CDD:477761	99/470 (21%)