Protein Alignment Cyp6a9 and Cyp4f39

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_796281.1
• Gene: Cyp4f39 / 320997
• MGIID: 2445210
• Length: 532
• Species: Mus musculus
• Alignment Length: 572
• Identity: 127/572 - (22%)
• Similarity: 233/572 - (40%)
• Gaps: 140/572 - (24%)

  Fly     3 VYSVLLAIVVVLVGYLLLKWRRALHYWQNLDIPCE------EP---HILMGSLT-------GVQ- 50
            |.|.||.:|:.....||:   ||...:.:..|.|.      ||   |.|:|.::       |:|
Mouse    23 VVSALLLLVLFFFFRLLV---RAFKLFSDFRITCRKLSCFPEPPGRHWLLGHMSMYLPNEKGLQN 84

  Fly    51 ------TSRSFSAIWMDYYNKFRGTGPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYH 109
                  |.......|:         |||........|..:...:..:..|..|:       .|::
Mouse    85 EKKVLDTMHHIILAWV---------GPFLPLLVLVHPDYIKPVLGASAAIAPKD-------EFFY 133

  Fly   110 NTEDDPLSGQLFLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQA--------- 165
            :.....|...|.:..|.||...|..|:..|....:|           .::::|.|.
Mouse   134 SFLKPWLGDGLLISKGNKWSRHRRLLTPAFHFDILK-----------PYMKIFNQCTNIMHAKWR 187

  Fly   166 --MEKSPIV--EVRDILARFTTDVIGTCAFGI--ECSS-LKDPEAEFRVMGRRAIFEQRHGPIGI 223
              :.:..:.  ::.:.::..|.|.:..|.|..  :|.. :.|
Mouse   188 RHLAEGSVTSFDMFEHISLMTLDSLQKCVFSYNSDCQERMSD----------------------- 229

  Fly   224 AFINSFQNLAR-------RLH---------------MKITLEEAEHFFLRIVRE---------TV 257
             :|:|...|:.       |||               .:...:...:|...:::|         ..
Mouse   230 -YISSIIELSALVVRRQYRLHHYLDFMYYLTADGRRFRQACDTVHNFTTEVIQERRQALRQQGAE 293

  Fly   258 AFREKNNIRRNDFMDQLIDLKNSPLTKSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALY 322
            |:.:....:..||:|.|:      |.|.|.|:  .|:.|::.|:|..|...|.:|:|:.:.:||:
Mouse   294 AWLKAKQGKTLDFIDVLL------LAKDEEGK--ELSDEDIRAEADTFMFEGHDTTSSGLSWALF 350

  Fly   323 ELAQHQDIQDRVRKECQEVI-GKYNGEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYE 386
            .||::.:.|::.|:|.|||: |:...|:.::.:..:.:....|.|:||.:..:.:::|.|.||.:
Mouse   351 NLAKYPEYQEKCREEIQEVMKGRELEELDWDDLTQLPFTTMCIKESLRQFPPVTLISRRCTEDIK 415

  Fly   387 VP-GHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCI 450
            :| |.   ||.||:..|:.....|.:..::.:...:||..|.|:..::|..:.::||..||||||
Mouse   416 LPDGR---VIPKGIICLVSIYGTHHNPIVWPDSKVYNPYRFDPDTPQQRSPLAFVPFSAGPRNCI 477

  Fly   451 GMRFGQMQARSGLALLINRFKFSVCEQTTIPIVYSKKTFLISSETGIFLKVE 502
            |..|...:.|..:||.:.||:.|| ::|  ..|..|...::.:|.|::|.||
Mouse   478 GQSFAMAEMRVVVALTLLRFRLSV-DRT--HKVRRKPELILRTENGLWLNVE 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	104/478 (22%)
Cyp4f39	NP_796281.1	CYP4F	82..523	CDD:410772	107/505 (21%)