Protein Alignment Cyp6a9 and Cyp4a3

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_038965516.1
• Gene: Cyp4a3 / 298423
• RGDID: 631356
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 537
• Identity: 142/537 - (26%)
• Similarity: 237/537 - (44%)
• Gaps: 89/537 - (16%)

  Fly     7 LLAIVVVLVG----YLLLKW-RRALHYWQNLDIPCEEPHILMGSLTGVQTSRSFSAI--WMDYYN 64
            ||::.:||..    ||..:| .:||.     ..|....|.|.|.   ....|.|..:  |::
  Rat    24 LLSLFLVLFKAVQFYLRRQWLLKALE-----KFPSTPSHWLWGH---DLKDREFQQVLTWVE--- 77

  Fly    65 KFRGTGPFAGFYWF--QRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSGQ---LFLLD 124
            ||    |.|...|.  .:..:|:.|....|::|.:...|.:  |.|.......:||.   |.||:
  Rat    78 KF----PGACLQWLSGSKTRVLLYDPDYVKVVLGRSDPKAS--GIYQFLAPWIVSGTGYGLLLLN 136

  Fly   125 GQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEK-----SPIVEVRDILARFTTD 184
            |:||......|:..|..|.:|    ..||:..:.:.:.....||     .|: |:...::..|.|
  Rat   137 GKKWFQHWRMLTPAFHYGILK----PYVKIMADSVSIMLDKWEKLDDQDHPL-EIFHYVSLMTLD 196

  Fly   185 VIGTCAFGIECSSLKDPEAE--------------FRVMGRRAIFEQRHGPIGIAFINSFQNLARR 235
            .:..|||..:.|...|..:.              |||   |:.|   :|...|..::|...|:||
  Rat   197 TVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLTFFRV---RSAF---YGNSIIYNMSSDGRLSRR 255

  Fly   236 L------HMK--ITLEEAEHFFLRIVRETVAFREKNNIRRNDFMDQLIDLKNSPLTKSESGESVN 292
            .      |..  |.:.:|:   |:...|....|:|.::   ||:|.|:      ..|.|.|:|
  Rat   256 ACQIAHEHTDGVIKMRKAQ---LQNEEELQKARKKRHL---DFLDILL------FAKMEDGKS-- 306

  Fly   293 LTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEITYESMKDM 357
            |:.|::.|:...|...|.:|:::.:.:..|.||.|.:.|:|.|:|.|.::|. ...:|::.:..:
  Rat   307 LSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGD-GTSVTWDHLDQI 370

  Fly   358 VYLDQVISETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFN 422
            .|....|.|.||||..:|.::||.......|....  |.||:...|....:|.:...:.||..|:
  Rat   371 SYTTMCIKEALRLYPPVPSVSRELSSPVTFPDGRS--IPKGITTTILIYGLHHNPSYWPNPKVFD 433

  Fly   423 PDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVCEQTTIPIVYSKK 487
            |..|||:  ..|.|..:|||..|.|||||.:|...:.:..:||.:.||:. :.:.|.||:..::
  Rat   434 PSRFSPD--SPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFEL-LPDPTRIPVPMAR- 494

  Fly   488 TFLISSETGIFLKVERV 504
             .::.|:.||.|:::::
  Rat   495 -LVLKSKNGIHLRLKKL 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	122/461 (26%)
Cyp4a3	XP_038965516.1	CYP4B-like	69..506	CDD:410771	127/478 (27%)